Characteristics and long-term health outcomes of the first domestic COVID-19 outbreak cases in Da Nang, Vietnam: a longitudinal cohort study

鶴岡, 美幸

doi:10.1186/s41182-024-00670-9

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Characteristics and long-term health outcomes of the first domestic COVID-19 outbreak cases in Da Nang, Vietnam: a longitudinal cohort study

http://hdl.handle.net/10069/0002002451

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ISYK1698_Tsuruoka.pdf (1.1 MB)

アイテムタイプ

学位論文 / Thesis or Dissertation(1)

公開日

2025-06-16

タイトル

Characteristics and long-term health outcomes of the first domestic COVID-19 outbreak cases in Da Nang, Vietnam: a longitudinal cohort study

言語

eng

キーワード

言語

主題Scheme

Other

主題

SARS-CoV-2

キーワード

言語

主題Scheme

Other

主題

COVID-19

キーワード

言語

主題Scheme

Other

主題

Long COVID

キーワード

言語

主題Scheme

Other

主題

Vietnam

キーワード

言語

主題Scheme

Other

主題

Wuhan strain

資源タイプ

資源タイプ識別子

http://purl.org/coar/resource_type/c_db06

資源タイプ

doctoral thesis

アクセス権

open access

アクセス権URI

http://purl.org/coar/access_right/c_abf2

著者

鶴岡, 美幸

著者別名

姓名

Tsuruoka, Miyuki

言語

抄録

内容記述タイプ

Other

内容記述

Background: Vietnam experienced the first COVID-19 domestic outbreak due to the Wuhan strain (B.1.1) in Da Nang from July 2020. COVID-19 can cause acute as well as long-term health problems. We aimed to characterise clinical features and risk factors related to severe illness of COVID-19 among Da Nang outbreak cases and to describe long-term health outcomes among survivors of this outbreak. Methods: We conducted an ambidirectional cohort study. Study subjects were all hospitalised cases with positive real-time PCR test of SARS-CoV-2 in the three major hospitals in Da Nang from 25 July to 28 August 2020. Clinical and demographic information was retrospectively collected from medical charts. Then, the survivors were followed-up prospectively at 6 and 16 months after acute infection to assess their health status via standardized questionnaires, physical examinations, chest X-rays and pulmonary function tests. Results: A total of 362 cases including 20 fatal cases were enrolled into the study retrospectively. The median age of the participants included in the medical chart review was 46.5 years and 60.8% were female. Overall, 7.8% of the participants required respiratory support during hospitalisation and 20 of them died. Compared to the survivors, the fatal cases were significantly older (median age of survivors 45.0 yr vs fatal cases 66.5 yr, P < 0.001) and more likely to have underlying conditions. The proportions of participants who had at least one long COVID symptom within the 7 days of each follow-up at 6 and 16 months were 72.0% (134/186) and 63.5% (47/74), respectively. We also found that females and adults reported symptoms more often in the follow-up surveys, 78.9% (90/114) [females] vs 61.1% (44/72) [males] at 6 months, P = 0.008; 68.7% (46/67) [20 years] vs 14.3% (1/7) 20 years] at 16 months, P = 0.004. Conclusions: In the first domestic COVID-19 outbreak in Vietnam, the mortality rate was approximately 6% and associated with underlying medical conditions. In the follow-up surveys, a substantial proportion of participants reported long COVID related health problems, although the prevalence declined over time. Females and adults reported symptoms more often, which might be due to the pathophysiological differences according to sex and age.

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内容記述

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内容記述

長崎大学学位論文学位記番号:博(医歯薬)甲第1698号学位授与年月日:令和7年3月19日

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内容記述

Author: Miyuki Tsuruoka, Mai Kim Huynh, Michiko Toizumi1, Thanh Tien Hoang, Trieu Bao Nguyen, Anh The Dao, Luong Dinh Nguyen, Huy Xuan Le, Chung Thanh Le, Anh Quang Dang, Hung Thai Do and Lay Myint Yoshida

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Citation: Tropical Medicine and Healthm, 53, art. no. 6; 2025

言語

書誌情報

en : Tropical Medicine and Health

巻 53, p. art. no. 6, 発行日 2025-03-19

ISSN

収録物識別子タイプ

ISSN

収録物識別子

1349-4147

DOI

関連識別子

10.1186/s41182-024-00670-9

権利

権利情報

© The Author(s) 2024. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

言語

著者版フラグ

出版タイプ

VoR

出版タイプResource

http://purl.org/coar/version/c_970fb48d4fbd8a85

その他のタイトル

ベトナム中部ダナン市におけるCOVID-19罹患後生存者の健康状況に関する縦断的観察研究

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出版者

BioMed Central Ltd

言語

関係URI

識別子タイプ

HDL

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2025-06-16 02:44:32.115447

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Characteristics and long-term health outcomes of the first domestic COVID-19 outbreak cases in Da Nang, Vietnam: a longitudinal cohort study

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Characteristics and long-term health outcomes of the first domestic COVID-19 outbreak cases in Da Nang, Vietnam: a longitudinal cohort study

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