| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2025-10-09 |
| タイトル |
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|
タイトル |
Dabigatran‐induced esophagitis with full circumferential blue pigmentation |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
atrial fibrillation |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
dabigatran |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
drug-related side effects and adverse reactions |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
esophagitis |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
pigmentation disorders |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Araki, Tomonori
Hayashi, Kohei
Sonoda, Yuki
Honda, Takuya
Imamura, Yoshifumi
Koide, Yuji
Hamada, Hisayuki
Nakao, Kazuhiko
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Dabigatran is a useful and widely used drug for stroke prevention in patients with atrial fibrillation. However, it has been reported to cause esophagitis. Herein, we report the case of a 77-year-old man with dabigatran-induced esophagitis with blue pigmentation, which is known to be a rare adverse effect. The patient presented to our hospital with a tightness of the chest and anorexia. Computed tomography revealed a thickening of the entire esophageal wall, with an upper esophageal predominance. Esophagogastroduodenoscopy was performed, which showed that the cervical and upper thoracic esophagus had blue pigmentation with edematous changes, partial narrowing, and longitudinal sloping. We replaced dabigatran with edoxaban, a similar anticoagulation medication. The patient was closely monitored for 1 month after switching to edoxaban. The follow-up esophagogastroduodenoscopy showed marked improvements, revealing resolution of the bluish discoloration and edematous changes, and the patient's complaints regarding the tightness of the chest and anorexia were also resolved. It is important to recognize that such side effects can occur with dabigatran, a drug that is frequently used in daily practice. Considering the fact that strong edematous changes can cause indigo carmine pigmentation associated with dabigatran stagnation, we recommend switching to another anticoagulant if esophagitis occurs during dabigatran administration. |
|
言語 |
en |
| 書誌情報 |
en : DEN Open
巻 4,
号 1,
p. art. no. e271,
発行日 2025-07-17
|
| 出版者 |
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|
出版者 |
John Wiley & Sons Australia, Ltd |
|
言語 |
en |
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
2692-4609 |
| DOI |
|
|
関連タイプ |
isIdenticalTo |
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|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.1002/DEO2.271 |
| 権利 |
|
|
権利情報 |
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. © 2023 The Authors. DEN Open published by John Wiley & Sons Australia, Ltd on behalf of Japan Gastroenterological Endoscopy Society. |
|
言語 |
en |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 引用 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
DEN Open, 4(1), art. no. e271; 2025 |
|
言語 |
en |
DENO4_e271.pdf (3.3 MB)
