| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2025-11-07 |
| タイトル |
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|
タイトル |
Clinical characteristics and prognosis of pulmonary aspergillosis complicating interstitial lung diseases |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Interstitial lung diseases (ILDs) |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Aspergillosis |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Chronic pulmonary aspergillosis |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Prognosis |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Ito, Yuya
Takazono, Takahiro
Yura, Hirokazu
Yoshida, Masataka
Takeda, Kazuaki
Ide, Shotaro
Iwanaga, Naoki
Sakamoto, Noriho
Yanagihara, Katsunori
Mukae, Hiroshi
|
| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
Background: Pulmonary aspergillosis can complicate interstitial lung diseases (ILDs) during immunosuppressive treatment. This study aimed to clarify the clinical characteristics and prognostic differences of pulmonary aspergillosis in patients with ILDs by disease subtypes. Methods: Patients diagnosed with both ILDs and pulmonary aspergillosis were retrospectively analyzed at Nagasaki University Hospital between October 1, 2008, and March 31, 2022. Pulmonary aspergillosis was categorized as invasive pulmonary aspergillosis (IPA) or chronic pulmonary aspergillosis (CPA). CPA was further subdivided into simple pulmonary aspergilloma (SPA), chronic cavitary pulmonary aspergillosis (CCPA), and subacute invasive aspergillosis (SAIA). Clinical characteristics and prognostic outcomes were compared among the subtypes. Results: Fifty patients with both diseases were analyzed: 38 had CPA and 12 had IPA. All patients with IPA had a history of corticosteroid use and a significantly higher prevalence of diabetes mellitus than those with CPA. In contrast, honeycombing changes on chest computed tomography (CT) were more frequently observed in patients with CPA than in those with IPA. Kaplan–Meier analysis showed that patients with IPA had significantly higher mortality rates than those with CPA, and that among CPA subtypes, patients with SAIA had significantly higher mortality rates than those with SPA or CCPA. Univariate analysis showed that the presence of SAIA or IPA was significantly associated with 1-year mortality compared to other subtypes. The type of underlying ILD did not affect the prognosis. Conclusions: Clinical characteristics and prognoses of pulmonary aspergillosis in patients with ILDs vary by subtype. |
|
言語 |
en |
| 書誌情報 |
en : Respiratory Investigation
巻 63,
号 6,
p. 1293-1299,
発行日 2025-10-23
|
| 出版者 |
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|
出版者 |
Elsevier B.V. |
|
言語 |
en |
| ISSN |
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|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
22125345 |
| DOI |
|
|
関連タイプ |
isVersionOf |
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|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.1016/j.resinv.2025.10.010 |
| 権利 |
|
|
権利情報 |
© 2025 The Japanese Respiratory Society. Published by Elsevier B.V. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/. |
|
言語 |
en |
| 著者版フラグ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 引用 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Respiratory Investigation, 63(6), pp.1293-1299; 2025 |
|
言語 |
en |
RI63_1293.pdf (770 KB)
