| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2026-01-09 |
| タイトル |
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|
タイトル |
Risk factors for bacterial translocation after loop ileostomy closure in patients with colorectal cancer |
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言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Bacterial translocation |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Colorectal cancer |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Loop ileostomy closure |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Postoperative complications |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 著者 |
Adachi, Toshiyuki
Inoue, Yusuke
Okada, Satomi
Miyoshi, Takayuki
Ueki, Nozomi
Kurohama, Hirokazu
Matsuoka, Yuki
Soyama, Akihiko
Kobayashi, Kazuma
Adachi, Tomohiko
Kanetaka, Kengo
Eguchi, Susumu
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| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
Purpose: Although rare, septic shock can develop following the closure of an ileostomy created during colorectal cancer surgery. In such cases, bacterial translocation (BT) is considered the primary diagnosis, and appropriate treatment is provided. Herein, we investigated the risk factors of BT following ileostomy closure after colorectal cancer surgery. Methods: A retrospective analysis was conducted using the colorectal cancer database of Nagasaki University, focusing on 91 patients who received ileostomy closure after colorectal cancer surgery. The patients were divided into two groups based on the occurrence of BT, defined as fever exceeding 38 °C without an identifiable cause, and data regarding patient background, surgical factors, and postoperative factors were assessed. Results: BT occurred in 12 of 91 patients. No significant differences were observed between the groups of patients in terms of background factors but C-reactive protein levels on postoperative days 3 and 7 were significantly higher in the BT group than in the non-BT group (BT group vs. non-BT group [median], day 3: 6.64 mg/dL vs. 3.79 mg/dL, p = 0.0026; day 7: 5.10 mg/dL vs. 1.52 mg/dL, p = 0.0007). Additionally, the rate of postoperative adjuvant chemotherapy administration was significantly higher in the BT than in the non-BT group (BT group vs. non-BT group: 83.3% vs. 43.0%, p = 0.0123). The pathological findings from resected specimens showed that mucosal height was lower in the anal side than in the oral side. Conclusion: Adjuvant chemotherapy may significantly increase the risk of BT after ileostomy closure following colorectal cancer surgery. |
|
言語 |
en |
| 書誌情報 |
en : International Journal of Colorectal Disease
巻 40,
号 1,
p. art. no. 248,
発行日 2025-12-18
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| 出版者 |
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出版者 |
Springer Nature |
|
言語 |
en |
| ISSN |
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|
収録物識別子タイプ |
EISSN |
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収録物識別子 |
1432-1262 |
| DOI |
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|
関連タイプ |
isIdenticalTo |
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|
識別子タイプ |
DOI |
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|
関連識別子 |
https://doi.org/10.1007/s00384-025-05040-3 |
| 権利 |
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|
権利情報 |
© The Author(s) 2025 This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and repro- duction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/. |
|
言語 |
en |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 引用 |
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内容記述タイプ |
Other |
|
内容記述 |
International Journal of Colorectal Disease, 40(1), art. no. 248; 2025 |
|
言語 |
en |
IJCD40_248.pdf (1.2 MB)
