| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2026-02-10 |
| タイトル |
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|
タイトル |
Rapid Typing of Extended‐Spectrum β‐Lactamase (ESBL)‐ and Metallo‐β‐Lactamase (MBL)‐Producing Enterobacterales Using Fourier Transform Infrared (FT‐IR) Spectroscopy |
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言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
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|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
antimicrobial resistance |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
molecular typing |
| キーワード |
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|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
outbreak |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
phenotypic similarity |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Kawamoto, Yasuhide
Kosai, Kosuke
Murata, Mika
Ota, Kenji
Mitsumoto‐Kaseida, Fujiko
Kaku, Norihito
Hasegawa, Hiroo
Izumikawa, Koichi
Mukae, Hiroshi
Yanagihara, Katsunori
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| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
This study investigated the usefulness of the IR Biotyper, which types bacterial strains using Fourier transform infrared (FT-IR) spectroscopy, against extended-spectrum β-lactamase (ESBL)- and metallo-β-lactamase (MBL)-producing Enterobacterales. Sixty-six clinical isolates (20 ESBL-producing Klebsiella pneumoniae, 15 IMP-producing K. pneumoniae, and 31 IMP-producing Enterobacter cloacae complex isolates) were analyzed using the IR Biotyper, pulsed-field gel electrophoresis (PFGE), multilocus sequence typing (MLST), and whole-genome single-nucleotide polymorphism (wgSNP) analyses and the results were compared. Of the 20 ESBL-producing K. pneumoniae strains analyzed, the IR Biotyper detected three clusters. Of these clusters, two were determined as respective clusters by PFGE and wgSNP analyses, and the strains included in each cluster showed the same STs. The IR Biotyper detected three clusters in the analysis of 15 IMP-producing K. pneumoniae strains. Of these clusters, strains in the two clusters showed high concordance with PFGE, MLST, and wgSNP analyses. The IR Biotyper identified six clusters among the IMP-producing E. cloacae complex isolates. These results were fully concordant with those of PFGE, MLST, and wgSNP analyses in the two clusters. The range of adjusted Rand index was 0.734–0.967 between the IR Biotyper and PFGE and 0.658–0.857 between the IR Biotyper and MLST or wgSNP analyses. This study demonstrated the performance of IR Biotyper for the detection of clonal similarities in ESBL- and IMP-producing Enterobacterales and it might be useful for outbreak investigation. |
|
言語 |
en |
| 書誌情報 |
en : MicrobiologyOpen
巻 15,
号 1,
p. art. no. e70218,
発行日 2026-02-02
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| 出版者 |
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出版者 |
John Wiley and Sons Inc |
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言語 |
en |
| ISSN |
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|
収録物識別子タイプ |
ISSN |
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収録物識別子 |
2045-8827 |
| DOI |
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|
関連タイプ |
isIdenticalTo |
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|
識別子タイプ |
DOI |
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|
関連識別子 |
https://doi.org/10.1002/mbo3.70218 |
| 権利 |
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|
権利情報 |
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. © 2026 The Author(s). MicrobiologyOpen published by John Wiley & Sons Ltd. |
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言語 |
en |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 引用 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
MicrobiologyOpen, 15(1), art. no. e70218; 2026 |
|
言語 |
en |
MO15_e70218.pdf (1.2 MB)
