| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2026-02-15 |
| タイトル |
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タイトル |
Total Syntheses of (+)-Penicibilaenes A and B via Enantioselective Desymmetrization |
|
言語 |
en |
| 言語 |
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|
言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 著者 |
Iwanaga, Taiga
Kishimoto, Satoshi
Fukuda, Hayato
Komine, Keita
Ishihara, Jun
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| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
Stereocontrolled total syntheses of (+)-penicibilaenes A and B were accomplished through three key steps: (1) Pd-catalyzed enantioselective desymmetrization to afford a pivotal chiral intermediate having an all-carbon quaternary stereogenic center, (2) ring-closing metathesis to form the bicyclo[3.3.1]nonane core, and (3) intramolecular nitrile oxide [3 + 2] cycloaddition to assemble the tricyclo[6.3.1.01,5]dodecane skeleton. Enantioselective desymmetrization delivered a highly functionalized cyclohexene, which provided access to (+)-penicibilaenes A and B. |
|
言語 |
en |
| 書誌情報 |
en : Organic Letters
巻 28,
号 4,
p. 1452-1456,
発行日 2026-01-19
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| 出版者 |
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出版者 |
American Chemical Society |
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言語 |
en |
| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
1523-7060 |
| DOI |
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|
関連タイプ |
isVersionOf |
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|
識別子タイプ |
DOI |
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|
関連識別子 |
https://doi.org/10.1021/acs.orglett.5c05356 |
| 権利 |
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|
権利情報 |
This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic letters, copyright © 2026 American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.orglett.5c05356 |
|
言語 |
en |
| 著者版フラグ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 引用 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Organic letters, 28(4), pp.1452-1456; 2026 |
|
言語 |
en |
OL28_1452.pdf (817 KB)
