| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2026-02-17 |
| タイトル |
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|
タイトル |
Effectiveness of maintaining oxygenation of a new high flow nasal cannula for endoscopic retrograde cholangiopancreatography during intravenous anesthesia |
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言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Hypoxemia |
| キーワード |
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|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Intravenous anesthesia |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
High-flow nasal cannula |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Endoscopic retrograde cholangiopancreatography |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Takahashi, Kosuke
Ozawa, Eisuke
Hiroshima, Yasuhisa
Sagami, Ryota
Hinokuchi, Makoto
Murakami, Masatoshi
Fujimori, Nao
Koga, Takehiko
Ishida, Yusuke
Ayuse, Takao
Miyaaki, Hisamitsu
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| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
Background: Intravenous anesthesia during endoscopic retrograde cholangiopancreatography (ERCP) is associated with a high incidence of respiratory depression. High-flow nasal cannula (HFNC) therapy uses a mild positive pressure load to enhance carbon dioxide washout and reduce rebreathing, thereby improving respiratory function. Therefore, it is widely used to prevent hypoxemia and hypercapnia. We aim to investigate the efficacy of a new HFNC device (AIRVO 3™) in improving respiratory status during sedated ERCP. Methods: In a multicenter randomized controlled study involving two groups—the HFNC and low-flow nasal cannula (LFNC) groups, adult patients undergo ERCP under sedation. For sedation, either the dexmedetomidine or midazolam protocol is used according to the guidelines. Pethidine hydrochloride and pentazocine are administered intravenously as analgesics. The primary endpoint is the incidence of hypoxemia, defined as peripheral oxygen saturation (SpO₂) ≤ 90% during intravenous anesthesia. As a secondary outcome, percutaneous CO2 concentration is measured to assess the device’s effectiveness in preventing hypercapnia. Furthermore, sedative and analgesic doses are evaluated to determine whether device use helps prevent the occurrence of hypercapnia and hypoxemia. Discussion: This study aims to generate evidence supporting the utility of HFNC as a potential therapeutic device for ERCP under sedation by determining whether the incidence rates of hypercapnia and hypoxemia are lower in the HFNC group than in the LFNC group. Trial registration {2a,2b}: The study was registered as jRCTs072240096 on January 16, 2025. |
|
言語 |
en |
| 書誌情報 |
en : Trials
巻 27,
号 1,
p. art. no. 119,
発行日 2026-01-13
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| 出版者 |
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出版者 |
BioMed Central Ltd |
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言語 |
en |
| ISSN |
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収録物識別子タイプ |
EISSN |
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収録物識別子 |
1745-6215 |
| DOI |
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|
関連タイプ |
isIdenticalTo |
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|
識別子タイプ |
DOI |
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|
関連識別子 |
https://doi.org/10.1186/s13063-025-09421-5 |
| 権利 |
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|
権利情報 |
© The Author(s) 2026. Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/. |
|
言語 |
en |
| 著者版フラグ |
|
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出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 引用 |
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内容記述タイプ |
Other |
|
内容記述 |
Trials, 27(1), art. no. 119; 2026 |
|
言語 |
en |
T27_119.pdf (1.1 MB)
