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  1. 120 熱帯医学研究所 = Institute of Tropical Medicine
  2. 120 学術雑誌論文 = Articles in academic journal

Incidence of COVID-19-Associated Hospitalization by Vaccination Status in Children and Adolescents During Omicron-Dominant Period in Japan: The VENUS Study

http://hdl.handle.net/10069/0002003883
http://hdl.handle.net/10069/0002003883
bb2cff8c-8195-4e69-b731-f06992040e73
名前 / ファイル ライセンス アクション
C13_183.pdf C13_183.pdf (735 KB)
アイテムタイプ 学術雑誌論文 / Journal Article(1)
公開日 2026-04-07
タイトル
タイトル Incidence of COVID-19-Associated Hospitalization by Vaccination Status in Children and Adolescents During Omicron-Dominant Period in Japan: The VENUS Study
言語 en
言語
言語 eng
キーワード
言語 en
主題Scheme Other
主題URI COVID-19
キーワード
言語 en
主題Scheme Other
主題URI SARS-CoV-2
キーワード
言語 en
主題Scheme Other
主題URI vaccination
キーワード
言語 en
主題Scheme Other
主題URI children
キーワード
言語 en
主題Scheme UDC
主題URI adolescents
キーワード
言語 en
主題Scheme UDC
主題URI hospitalization
キーワード
言語 en
主題Scheme Other
主題URI Omicron
キーワード
言語 en
主題Scheme Other
主題URI Japan
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 Maeda, Haruka

× Maeda, Haruka

en Maeda, Haruka

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Toizumi, Michiko

× Toizumi, Michiko

en Toizumi, Michiko

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Igarashi, Ataru

× Igarashi, Ataru

en Igarashi, Ataru

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Maeda, Megumi

× Maeda, Megumi

en Maeda, Megumi

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Oda, Futoshi

× Oda, Futoshi

en Oda, Futoshi

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Fukuda, Haruhisa

× Fukuda, Haruhisa

en Fukuda, Haruhisa

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抄録
内容記述タイプ Abstract
内容記述 Background/Objectives: Evidence regarding the impact of COVID-19 vaccination on children and adolescents remains limited, particularly in Japan. Thus, this study aimed to estimate incidence rates of COVID-19-associated hospitalization by vaccination status and evaluate the association between COVID-19 vaccination and COVID-19-associated hospitalization among individuals aged 6 months to <18 years in Japan. Methods: We conducted a retrospective, population-based cohort study using linked health insurance claims data and municipal COVID-19 vaccination registry records from nine Japanese municipalities between 1 January 2022, and 31 March 2023, when the Omicron variant was dominant nationwide. Incidence rates of COVID-19-associated hospitalization were estimated among unvaccinated individuals and those who had received one dose (partially vaccinated) or at least two doses of an ancestral monovalent COVID-19 vaccine (fully vaccinated). Incidence rate ratios (IRRs) were calculated, adjusting for age group, sex, presence of underlying medical conditions, municipality, and calendar month. Results: Among 163,305 individuals, 93 COVID-19-associated hospitalizations were identified. Crude incidence rates were 4.5 (95% confidence interval [CI]: 3.6–5.6), 3.2 (95% CI: 0.1–18.0), and 2.3 (95% CI: 1.1–4.2) per 100,000 person-months in unvaccinated, partially, and fully vaccinated groups, respectively. The adjusted IRR for the fully vaccinated group was 0.429 (95% CI: 0.198–0.930). Among hospitalized patients, 30.1% had underlying medical conditions, and only 4.3% required oxygen administration during hospitalization. Conclusions: Receiving at least two doses of COVID-19 vaccine was associated with a lower incidence rate of COVID-19-associated hospitalization among children and adolescents during the Omicron-dominant period in Japan. Expanding vaccine uptake among eligible pediatric populations may help reduce the burden of severe disease.
言語 en
書誌情報 en : Children

巻 13, 号 2, p. art. no. 183, 発行日 2026-01-28
出版者
出版者 MDPI
言語 en
ISSN
収録物識別子タイプ ISSN
収録物識別子 2227-9067
DOI
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 https://doi.org/10.3390/children13020183
権利
権利情報 © 2026 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.
言語 en
著者版フラグ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
引用
内容記述タイプ Other
内容記述 Children, 13(2), art. no. 183; 2026
言語 en
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