@article{oai:nagasaki-u.repo.nii.ac.jp:00020072,
 author = {Naito, Tatsuji and Miyahara, Yoshiyuki and Ikeda, Satoshi},
 issue = {4},
 journal = {Acta medica Nagasakiensia},
 month = {Dec},
 note = {The present study was undertaken to examine the pulmonary vascular and ventilatory responses to acute hypoxia in chronic obstructive lung disease. Pulmonary hemodynamics, minute ventilation (VE) and oxygen uptake (VO2) were serially measured during inhalation of 13 %O2 for 15 min. There was a wide variablility in the pulmonary, vascular response to acute hypoxia. ,The initial increase in VE and the magnitude of change in VO2 were significantly lower in subjects developing a 25 % or great increase in mean pulmonary arterial pressure during hypoxic breathing. These results suggest that the ventilatory response to acute hypoxia plays a significant role in the pulmonary vascular response to acute hypoxia, and blunted initial ventilatory response to acute hypoxia may be a physiological adaptation to enhanced responses of pulmonary vessels., Acta medica Nagasakiensia. 1994, 39(4), p.82-86},
 pages = {82--86},
 title = {Ventilatory and Pulmonary Vascular Responses to Acute Hypoxia in Patients with Chronic Obstructive Lung Disease},
 volume = {39},
 year = {1994}
}