@article{oai:nagasaki-u.repo.nii.ac.jp:00020078, author = {Matsunaga, Kazuo and Miyahara, Yoshihisa and Harada, Takashi and Yamasa, Toshihiko and Imamura, Toshiyuki}, issue = {4}, journal = {Acta medica Nagasakiensia}, month = {Dec}, note = {In patients with chronic pulmonary disase (CPD), myocardial infarction is rare. To elucidate why this is so, we investigated the morphological changes and the reactivity of the coronary artery to acute hypoxia in patients with CPD. Sixty patients with CPD and 28 normal subjects were studied. Measurements of pulmonary homodynamics and coronary angiography were undertaken before and after inhalation of 13%O2 for 15 minutes. The size of the coronary arteries was measured using a densitometric method, and a coronary narrowing score was calculated according to the WHO criteria. The size of the left anterior descending artery of patients with low %VC and hypoxia was larger than that of the normal subjects. In patients with CPD, the coronary narrowing score was low and the atherosclerotic change was minimal. The reactivity of the coronary arteries to acute hypoxia was reduced in patients with CPD when compared with normal subjects., Acta medica Nagasakiensia. 1994, 39(4), p.119-124}, pages = {119--124}, title = {CORONARY ARTERY MORPHPLOGY AND REACTIVITY TO ACUTE HYPOXIA IN CHRONIC PULMONARY DISEASE}, volume = {39}, year = {1994} }