@article{oai:nagasaki-u.repo.nii.ac.jp:00000201, author = {Aikawa, Erika and Shimizu, Toshimasa and Koga, Tomohiro and Endo, Yushiro and Umeda, Masataka and Hori, Tomoko and Irie, Junji and Kuroda, Kishio and Eguchi, Mizuna and Okamoto, Momoko and Tsuji, Sosuke and Takatani, Ayuko and Igawa, Takashi and Sumiyoshi, Remi and Kawashiri, Shin-ya and Iwamoto, Naoki and Ichinose, Kunihiro and Tamai, Mami and Nakamura, Hideki and Origuchi, Tomoki and Kawakami, Atsushi}, issue = {12}, journal = {Internal Medicine}, month = {Jun}, note = {A 53-year-old man with recurrent episodes of large joint pain and a low-grade fever at irregular intervals for 16 years developed right knee and ankle arthralgia, watery diarrhea, and abdominal pain. Following an ileum and colon biopsy, he was diagnosed with gastrointestinal amyloidosis. We suspected familial Mediterranean fever (FMF) based on his history and administered colchicine; his symptoms subsequently improved. Thus, he was diagnosed with atypical FMF. After tocilizumab administration, the amyloid deposits disappeared. This case suggests that physicians should consider FMF even in cases with atypical symptoms in order to prevent the progression of amyloidosis and that amyloid deposits can be eliminated by interleukin (IL)-6 inhibition., Internal Medicine, 58(12), pp.1781-1785; 2019}, pages = {1781--1785}, title = {Atypical Familial Mediterranean Fever Complicated with Gastrointestinal Amyloidosis Diagnosed due to Paroxysmal Arthralgia and Intractable Diarrhea, Successfully Treated with Tocilizumab}, volume = {58}, year = {2019} }