@article{oai:nagasaki-u.repo.nii.ac.jp:00020157,
 author = {Atari, Eio and Toda, Takayoshi and Muktafisadi, Al and Egawa, Haruhiko and Moromizat, Hidehiko and Mamadi, Touye and Kiyuna, Masaya},
 issue = {1-2},
 journal = {Acta medica Nagasakiensia},
 month = {Jun},
 note = {To study the process of cell death in cervical squamous cell carcinoma (SCC) after radiation, an ultrastructural and immunohistochemical study was performed. Paraffinembedded tissue blocks of biopsy samples pre- and postradiation stage III SCC (n = 15) were collected. Irradiation caused varying ultrastructural changes including nuclear and cytoplasmic disorganization suggesting cell necrosis. Immunohistochemically, the pre-radiation specimens showed no positive reaction for tumor necrosis factor-alpha (TNF- ﾎｱ),tumor necrosis factor-receptor(TNF-ﾎｳ)or Fas. C-fos, p 53 and bcl-2 showed positive reactions in only a few nonirradiated specimens. All of the irradiated specimens showed a positive reaction for TNF-ﾎｱ,and variable positive reactions  were observed for TNF-ﾎｳ,Fas, p 53, c-fos and bcl-2. These results suggest that TNF-ﾎｱ,TNF-ﾎｳ,and c-fos are responsible for radiation induced cell death in cervical SCC., Acta medica Nagasakiensia. 1998, 43(1-2), p.38-43},
 pages = {38--43},
 title = {Radiation Induced Cell Death in Cervical Squamous Cell Carcinoma : An Immunohistochemical and Ultrastructural Study},
 volume = {43},
 year = {1998}
}