@article{oai:nagasaki-u.repo.nii.ac.jp:00020185, author = {Inada, Masataka and Yamasaki, Naoko and Higami, Yoshikazu and Shigeoka, Yuji and Yamaie, Jin and Shimokawa, Isao}, issue = {1-2}, journal = {Acta medica Nagasakiensia}, month = {Jun}, note = {Recent developments in radiologic imaging and thoracoscopic excision techniques have increased the possibility of encountering small, benign or premalignant tumors in the lung. In this report, we describe a rare case of papillary adenoma of type 2 pneumocytes. A 51-year-old Japanese woman was hospitalized following a traffic accident. Helical CT scan of the chest incidentally detected a nodular ground-glass opacity measuring 8 mm in diameter at the subpleural region of left lung. The nodule was thoracoscopically resected out. Light microscopic examination demonstrated a noninfiltrative tumor consisting of cuboidal cells covering fibrovascular cores; thus, the tumor exhibited a branching papillary appearance. The cuboidal cells showed little nuclear atypia. Mitotic figures, necrosis, and intercellular mucin were absent. The cytoplasm was immunohistochemically stained for surfactant apoprotein A and cytokeratin, though not for carcinoembryonic antigen (CEA), epithelial membrane antigen (EMA), or S100 protein. The morphologic and immunohistochemical findings fulfilled the criteria of papillary adenoma of type 2 pneumocytes., Acta medica Nagasakiensia. 1999, 44(1-2), p.33-36}, pages = {33--36}, title = {Papillary Adenoma of Type 2 Pneumocytes in the Lung}, volume = {44}, year = {1999} }