@article{oai:nagasaki-u.repo.nii.ac.jp:00020188, author = {Hashiyada, Hiroshi and Takagi, Masatake and Yamada, Takafumi and Kugimiya, Toshiyasu}, issue = {1-2}, journal = {Acta medica Nagasakiensia}, month = {Jun}, note = {The effects of a sleeve anastomotic technique (SL), which was designed to avoid intimal injury, on the healing characteristics of a polytetrafluoro-ethylene (PTFE) graft were compared with the effects of the conventional end-to-end anastomotic technique (ETE). A segment of canine abdominal aorta was replaced with a PTFE graft. The grafts were explanted after 4 months and the anastomotic portion was examined macroscopically and by light microscopy. The animals were divided into 4 groups (A to D) according to the combination of the anastomotic methods (ETE or SL) used for the proximal and distal anastomosis. No substantial difference was found between the proximal and distal anastomosis for either ETE or SL. The pulling tests between the PTFE graft and the excised segment of the abdominal aorta revealed no significant difference in the breaking loads between ETE and SL. Macroscopic and microscopic examination revealed that SL resulted in better and more regular neointimal extension on the luminal surface of the PTFE graft. The results suggest that SL is less traumatic to the endothelium of the host artery and may be effective in preventing postoperative intimal hyperplasia., Acta medica Nagasakiensia. 1999, 44(1-2), p.47-52}, pages = {47--52}, title = {An Experimental Study of the Sleeve Technique in Graft Anastomosis}, volume = {44}, year = {1999} }