@article{oai:nagasaki-u.repo.nii.ac.jp:00020192, author = {Sato, Shouichi and Murase, Kunihiko and Haraguchi, Masuho and Tanioka, Hajime and Yano, Yoshitsugu and Itsuno, Minoru and Asai, Sadahiro and Iwasaki, Keisuke and Ishikawa, Hiroshi and Isomoto, Hajime and Takeshima, Fuminao and Mizuta, Yohei and Kohno, Shigeru}, issue = {1-2}, journal = {Acta medica Nagasakiensia}, month = {Jun}, note = {Small, flat-type advanced colonic adenocarcinomas are rare. We present a case of small colonic carcinoma invading the subserosal layer. A 61-year-old asymptomatic man was admitted for further examination of positive occult blood test. Barium enema and endoscopic examination revealed a small (10 mm in diameter) flat lesion with elevated margins and a central depression, in the transverse colon. Biopsy specimen taken from the tumor showed poorly differentiated adenocarcinoma. Based on radiologic and endoscopic evaluation, a provisional diagnosis was made of colonic tumor with invasion of the deep submucosal layer. Surgical resection of the transverse colon was performed. The tumor was macroscopically a type IIa + IIc lesion measuring 10 mm in diameter. Histological examination showed poorly differentiated adenocarcinoma infiltrating the subserosal layer. Awareness of this type of tumor should allow early diagnosis and treatment, resulting in improved prognosis., Acta medica Nagasakiensia. 1999, 44(1-2), p.66-69}, pages = {66--69}, title = {Small Colonic Cancer with Invasion of the Subserosal Layer. Report of a Case}, volume = {44}, year = {1999} }