{"created":"2023-05-15T16:44:30.897350+00:00","id":20212,"links":{},"metadata":{"_buckets":{"deposit":"47987a12-1e9c-4b23-b4f8-1a88bf282ad4"},"_deposit":{"created_by":2,"id":"20212","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"20212"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00020212","sets":["29:30:1713167819629:1397"]},"author_link":["85390","85388","85394","85386","85392","85393","85389","85395","85387","85391","85385","85396"],"item_3_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2000-06-14","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-2","bibliographicPageEnd":"50","bibliographicPageStart":"47","bibliographicVolumeNumber":"45","bibliographic_titles":[{"bibliographic_title":"Acta medica Nagasakiensia"}]}]},"item_3_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Aims: We examined the preoperative serum levels of sialyl Lewisa (CA19-9) and carcinoembryonic antigen (CEA) in 262 colorectal cancer patients, in order to clarify whether or not the prognostic value of CA19-9 after curative surgery is superior to that of CEA. Patients and Methods: The patients were divided into two groups: low or high antigen groups (higher or lower than a selected diagnostic-based cut-off value). For evaluation of the prognostic value of CA19-9 and CEA, the disease-free interval was studied. Results: The disease-free interval of patients with a high serum levels of CA19-9 or CEA was significantly shorter than for those patients with a low serum level of the particular antigen (P<0.0001 and P=0.0009, respectively). The disease-free interval of patients with stage I/II tumors who had a high CA19-9 level was significantly shorter than in those patients with stage I/II tumors with low CA19-9 levels (P=0.0020). In contrast, the disease-free interval of patients with stage I/II tumors who had a low or high CEA level did not differ. Cox s regression analysis revealed that a high serum level of CA19-9 or CEA was an independent predictor for short disease-free interval after curative surgery, separate from stage (Hazard ratio=2.65 or 1.68, respectively, versus a low serum level of each respective antigen) . Conclusions: These data suggest that the preoperative serum level of CA19-9 was a stronger prognostic factor after curative surgery than CEA. Furthermore, in contrast to CEA, CA19-9 provides more prognostic information than that obtained by conventional staging methods in patients with stage I/II tumors.","subitem_description_type":"Abstract"}]},"item_3_description_64":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Acta medica Nagasakiensia. 2000, 45(1-2), p.47-50","subitem_description_type":"Other"}]},"item_3_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00508430","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00016055","subitem_source_identifier_type":"ISSN"}]},"item_3_text_62":{"attribute_name":"sortkey","attribute_value_mlt":[{"subitem_text_value":"P00047-P00050"}]},"item_3_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nakagoe, Tohru"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sawai, Terumitsu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tsuji, Takashi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Jibiki, Masaaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ohbatake, Masayuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakashima, Atsushi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamaguchi, Hiroyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kurosaki, Nobuko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yasutake, Toru"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ayabe, Hiroyoshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Miyashita, Hiroko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Arisawa, Kokichi"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-23"}],"displaytype":"detail","filename":"acta45_01_08_t.pdf","filesize":[{"value":"499.4 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"acta45_01_08_t.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/20212/files/acta45_01_08_t.pdf"},"version_id":"70e9f60e-720b-4f4e-a1d7-2705330e1dbe"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"CA19-9","subitem_subject_scheme":"Other"},{"subitem_subject":"Sialyl Lea","subitem_subject_scheme":"Other"},{"subitem_subject":"CEA","subitem_subject_scheme":"Other"},{"subitem_subject":"prognostic factor","subitem_subject_scheme":"Other"},{"subitem_subject":"colorectal cancer","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Prognostic Value of Circulating CA 19-9 in Colorectal Cancer Patients","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Prognostic Value of Circulating CA 19-9 in Colorectal Cancer Patients"}]},"item_type_id":"3","owner":"2","path":["1397"],"pubdate":{"attribute_name":"公開日","attribute_value":"2008-03-13"},"publish_date":"2008-03-13","publish_status":"0","recid":"20212","relation_version_is_last":true,"title":["Prognostic Value of Circulating CA 19-9 in Colorectal Cancer Patients"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2024-04-17T04:03:54.439616+00:00"}