@article{oai:nagasaki-u.repo.nii.ac.jp:00020215,
 author = {Alipov, Gabit and Nakashima, Masahiro and Ito, Masahiro and Matsuzaki, Sumihiro and Kusano, Hiroyuki and Sekine, Ichiro},
 issue = {1-2},
 journal = {Acta medica Nagasakiensia},
 month = {Jun},
 note = {A poorly differentiated adenocarcinoma containing diverse components, tubular, signet-ring cell and neuroendocrine elements, in a 79-year-old man is described. Endoscopy examination revealed a Borrmann type IV tumor in the antrum. Histologically, scattered foci of tubular and signet-ring cells and a greater number of neuroendocrine elements were observed. The tumor cells were positive for chromogranin A, neuron specific enolase (NSE) and carcinoembryonic antigen (CEA). Furthermore, about one third of the tumor cells were demonstrated as amphicrine differentiation by double staining with chromogranin A and periodic acid-Schiff (PAS). Amphicrine cell carcinomas with exocrine and endocrine differentiation in the stomach is rare and poor prognosis. The present case suggests that amphicrine cell carcinomas can occur in signet-ring cell morphogenesis, and that a multipotential stem cell is an origin of this unusual variant of neuroendocrine carcinoma., Acta medica Nagasakiensia. 2000, 45(1-2), p.67-69},
 pages = {67--69},
 title = {Signet-Ring Cell-Like Amphicrine Cell Carcinoma of the Stomach},
 volume = {45},
 year = {2000}
}