@article{oai:nagasaki-u.repo.nii.ac.jp:00020236,
 author = {Morikawa, Minoru and Kaminogo, Makio and Ishimaru, Hideki and Nakashima, Kazuaki and Kitagawa, Naoki and Kabasawa, Hiroyuki and Ochi, Makoto and Hayashi, Kuniaki and Shibata, Shobu},
 issue = {1-2},
 journal = {Acta medica Nagasakiensia},
 month = {Jun},
 note = {We describe and evaluate the findings of three-dimensional anisotropy contrast MR axonography (3DAC MRX) and functional MRI (fMRI) in brain tumor and infarction. We obtained diffusion-weighted images (DWI) in 28 patients including 23 brain tumors and 15 acute infarctions located in or near pyramidal tract. Three anisotropic DWIs were transformed into graduations color-coded as red, green or blue, and then composed to form a combined color 3DAC MRX. We also performed functional MRI in 7 of the 28 patients and compared with cortical mapping of 3DAC MRX. 3DAC MRX with 23 brain tumors showed that the ipsilateral pyramidal tract was either discontinuous due to impaired anisotropy (n=8) or compressed due to mass effect (n=15). In 10 patients of acute infarction with motor impairment, pyramidal tract involvement was visually more conspicuous on 3DAC MRX compared to standard DWI. On functional MRI, hand motor activation was observed between blue vertical directional colors of pre- and post central gyrus. In conclusion, 3DAC MRX is a new noninvasive approach for visualization of the white matter neuronal tract and provides the information concerning pyramidal tract involvement., Acta medica Nagasakiensia. 2001, 46(1-2), p.61-66},
 pages = {61--66},
 title = {Three-Dimensional Anisotropy Contrast MRI and Functional MRI of the Human Brain: Clinical Application to Assess Pyramidal Tract in Patients with Brain Tumor and Infarction},
 volume = {46},
 year = {2001}
}