{"created":"2023-05-15T16:44:33.680164+00:00","id":20260,"links":{},"metadata":{"_buckets":{"deposit":"31e77942-6b1b-4b71-94aa-490b57ebda07"},"_deposit":{"created_by":2,"id":"20260","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"20260"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00020260","sets":["29:30:1713167819629:1401"]},"author_link":["85693","85697","85700","85696","85694","85699","85695","85698"],"item_3_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2002-06-18","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-2","bibliographicPageEnd":"41","bibliographicPageStart":"37","bibliographicVolumeNumber":"47","bibliographic_titles":[{"bibliographic_title":"Acta medica Nagasakiensia"}]}]},"item_3_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Sialyl Lewisa (CA19-9) and sialyl LewisX antigens (CSLEXI) may play a role in tumor metastasis by serving as functional ligands in the cell adhesion system. To determine their prognostic value, we examined preoperative serum levels of CA19-9, CSLEXI, and carcinoembryonic antigen (CEA) in 64 female patients with primary breast cancer who underwent radical mastectomy. The patients were divided into two groups, termed the low- and high-antigen groups based on a value selected as a diagnostic cut-off. Correlation between the serum antigen levels, various established clinicopathologic factors, and prognosis were studied by univariate and multivariate analysis. The high- CEA group was at a more advanced stage (including T factor, N factor, M factor, and Stage) than the low-CEA group. Patients with high serum levels of CEA had shorter disease- specific intervals than those with low serum levels (P <0.0001), whereas disease-specific intervals did not differ between low- and high-CA19-9 or CSLEXI groups. A Cox's regression multivariate analysis revealed a high serum CEA level as an independent factor for worse outcome, separate from Stage. In conclusion, an elevated preoperative serum CEA level was a predictor for poor outcome after radical mastectomy for breast cancer, while CA19-9 and CSLEX1 were not.","subitem_description_type":"Abstract"}]},"item_3_description_64":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Acta medica Nagasakiensia. 2002, 47(1-2), p.37-41","subitem_description_type":"Other"}]},"item_3_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00508430","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00016055","subitem_source_identifier_type":"ISSN"}]},"item_3_text_62":{"attribute_name":"sortkey","attribute_value_mlt":[{"subitem_text_value":"P00037-P00041"}]},"item_3_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nakagoe, Tohru"}],"nameIdentifiers":[{"nameIdentifier":"85693","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Itoyanagi, Noriaki"}],"nameIdentifiers":[{"nameIdentifier":"85694","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ikuta, Yasushi"}],"nameIdentifiers":[{"nameIdentifier":"85695","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ayabe, Hiroyoshi"}],"nameIdentifiers":[{"nameIdentifier":"85696","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hara, Shinsuke"}],"nameIdentifiers":[{"nameIdentifier":"85697","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ishikawa, Hiroshi"}],"nameIdentifiers":[{"nameIdentifier":"85698","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Minami, Hiroyuki"}],"nameIdentifiers":[{"nameIdentifier":"85699","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Fukushima, Kiyoyasu"}],"nameIdentifiers":[{"nameIdentifier":"85700","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-23"}],"displaytype":"detail","filename":"acta47_01_06_t.pdf","filesize":[{"value":"562.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"acta47_01_06_t.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/20260/files/acta47_01_06_t.pdf"},"version_id":"b74a797b-f112-4047-b8a3-cc5aef450435"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"carcinoembryonic antigen","subitem_subject_scheme":"Other"},{"subitem_subject":"CEA","subitem_subject_scheme":"Other"},{"subitem_subject":"sialyl Lewisa","subitem_subject_scheme":"Other"},{"subitem_subject":"CA 19-9","subitem_subject_scheme":"Other"},{"subitem_subject":"sialyl LewisX","subitem_subject_scheme":"Other"},{"subitem_subject":"CSLEX 1","subitem_subject_scheme":"Other"},{"subitem_subject":"breast cancer","subitem_subject_scheme":"Other"},{"subitem_subject":"prognostic value","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Preoperative Serum Levels of Sialyl Lewisa, Sialyl Lewisx, and Carcinoembryonic Antigens as Prognostic Factors after Resection for Primary Breast Cancer","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Preoperative Serum Levels of Sialyl Lewisa, Sialyl Lewisx, and Carcinoembryonic Antigens as Prognostic Factors after Resection for Primary Breast Cancer"}]},"item_type_id":"3","owner":"2","path":["1401"],"pubdate":{"attribute_name":"公開日","attribute_value":"2008-03-13"},"publish_date":"2008-03-13","publish_status":"0","recid":"20260","relation_version_is_last":true,"title":["Preoperative Serum Levels of Sialyl Lewisa, Sialyl Lewisx, and Carcinoembryonic Antigens as Prognostic Factors after Resection for Primary Breast Cancer"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2024-04-17T04:02:29.640480+00:00"}