{"created":"2023-05-15T16:30:46.482375+00:00","id":2028,"links":{},"metadata":{"_buckets":{"deposit":"f6a490f2-14e0-4ef4-a614-f328a754d107"},"_deposit":{"created_by":2,"id":"2028","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"2028"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00002028","sets":["10:11"]},"author_link":["9325","9320","9318","9315","9319","9317","9326","9321","9324","9322","9323","9316"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-06-18","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"101485","bibliographicVolumeNumber":"39","bibliographic_titles":[{"bibliographic_title":"Stem Cell Research"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We established three iPSC lines from postmortem-cultured fibroblasts derived following the sudden unexpected death of an 8-year-old girl with Lennox-Gastaut syndrome,\n who turned out to have the R551H-mutant STXBP1 gene. These iPSC clones showed pluripotent characteristics while retaining the genotype and demonstrated trilineage differentiation capability, indicating their utility in disease-modeling studies, i.e., STXBP1-encephalopathy. This is the first report on the establishment of iPSCs from a sudden death child, suggesting the possible use of postmortem-iPSC technologies as an epoch-making approach for precise identification of the cause of sudden death.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Stem Cell Research, 39, art.no.101485; 2019","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier B.V."}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.scr.2019.101485","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"c 2019 Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/BY-NC-ND/4.0/)."}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"18735061","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Yamamoto, Takuma"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Otsu, Makoto"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Okumura, Takashi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Horie, Yumi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ueno, Yasuharu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Taniguchi, Hideki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ohtaka, Manami"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakanishi, Mahito"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Abe, Yuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Murase, Takehiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Umehara, Takahiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ikematsu, Kazuya"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-18"}],"displaytype":"detail","filename":"SCR39_101485.pdf","filesize":[{"value":"1.0 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"SCR39_101485.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/2028/files/SCR39_101485.pdf"},"version_id":"036e8baa-2ee5-4236-b03a-a7cf9c385ba0"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Generation of three induced pluripotent stem cell lines from postmortem tissue derived following sudden death of a young patient with STXBP1 mutation","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Generation of three induced pluripotent stem cell lines from postmortem tissue derived following sudden death of a young patient with STXBP1 mutation"}]},"item_type_id":"2","owner":"2","path":["11"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-07-23"},"publish_date":"2019-07-23","publish_status":"0","recid":"2028","relation_version_is_last":true,"title":["Generation of three induced pluripotent stem cell lines from postmortem tissue derived following sudden death of a young patient with STXBP1 mutation"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T03:54:03.946051+00:00"}