@article{oai:nagasaki-u.repo.nii.ac.jp:00020310, author = {Nakagoe, Tohru and Ishikawa, Hiroshi and Sawai, Terumitsu and Tsuji, Takashi and Hidaka, Shigekazu and Tanaka, Kenji and Takeshita, Hiroaki and Ohbatake, Masayuki and Nanashima, Atsushi and Akiyama, Shinji and Yamaguchi, Hiroyuki and Yasutake, Toru and Nagayasu, Takeshi and Kamihira, Shimeru}, issue = {3-4}, journal = {Acta medica Nagasakiensia}, month = {Dec}, note = {The aim of this study was to clarify whether or not preoperative serum levels of sialyl Lewisa (CA19-9), sialyl LewisX (SLX), and sialyl Tn (STN) antigens are predictors for diffuse type gastric cancer. Eighty-two patients with diffuse type and 96 patients with intestinal type cancers were studied. Univariate logistic regression analysis showed that the following factors were significantly associated with diffuse type cancer: high levels of serum STN, young age (<62 years), female gender, tumor in the middle stomach, macroscopic type 3/type 4 cancer, presence of lymphatic invasion, peritoneal dissemination, stage III/IV, and non-curative resection. Multivariate analysis revealed that diffuse type cancer was independently related to young age (<62 years), female gender, tumor in the middle stomach, and macroscopic type 3/type 4 cancer. In conclusion, none of the preoperative serum levels of CA19-9, SLX, and STN were predictors for diffuse type cancer., Acta medica Nagasakiensia. 2003, 48(3-4), p.129-133}, pages = {129--133}, title = {Circulating Sialyl Lewisa, Sialyl LewisX, and Sialyl Tn Antigens in Patients with Diffuse Type of Gastric Cancer}, volume = {48}, year = {2003} }