{"created":"2023-05-15T16:44:36.181519+00:00","id":20318,"links":{},"metadata":{"_buckets":{"deposit":"a413a016-0ca5-4db8-a82f-10eab8b94c69"},"_deposit":{"created_by":2,"id":"20318","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"20318"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00020318","sets":["29:30"]},"author_link":["86053","86055","86056","86051","86050","86054","86052","86057"],"item_3_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2003-12-24","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3-4","bibliographicPageEnd":"182","bibliographicPageStart":"179","bibliographicVolumeNumber":"48","bibliographic_titles":[{"bibliographic_title":"Acta medica Nagasakiensia"}]}]},"item_3_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Autoimmune hepatitis (AIH) is frequently associated with extrahepatic autoimmune disorders such as rheumatoid arthritis, Sjogren's syndrome, and chronic thyroiditis, but the association with idiopathic (immune) thrombocytopenic purpura (ITP) is rare. We report a 46-year-old Japanese woman who presented with severe thrombocytopenia, elevated levels of aminotransferases, immunoglobulin (Ig) G, and platelet-associated IgG (PAIgG), positive anti-nuclear antibody, and hypothyroidism. After a diagnosis of coexisting AIH, ITP, and chronic thyroiditis, the patient was treated with 30 mg/day of prednisolone orally. The patient responded to such treatment: showing an increase in the number of platelets and decrease of serum levels of aminotransferases, IgG, and PAIgG to within normal ranges. Discrimination of ITP from liver cirrhosis as a cause of severe thrombocytopenia seen in chronic liver disease is important because complications and therapy are quite different. Prednisolone as a treatment for All should be also effective for ITP, and therefore, ITP should be considered when liver dysfunction is accompanied by severe thrombocytopenia, particularly in the autoimmune types of liver diseases.","subitem_description_type":"Abstract"}]},"item_3_description_64":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Acta medica Nagasakiensia. 2003, 48(3-4), p.183-182","subitem_description_type":"Other"}]},"item_3_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00508430","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00016055","subitem_source_identifier_type":"ISSN"}]},"item_3_text_62":{"attribute_name":"sortkey","attribute_value_mlt":[{"subitem_text_value":"P00179-P00182"}]},"item_3_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kawano, Naoko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Omagari, Katsuhisa"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamanaka, Hideo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kadokawa, Yoshiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takamori, Kenichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Isomoto, Hajime"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Mizuta, Yohei"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kohno, Shigeru"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-23"}],"displaytype":"detail","filename":"acta48_03_15_t.pdf","filesize":[{"value":"482.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"acta48_03_15_t.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/20318/files/acta48_03_15_t.pdf"},"version_id":"bf381edb-d8de-4f14-bffe-34a3ec085041"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"autoimmune hepatitis","subitem_subject_scheme":"Other"},{"subitem_subject":"idiopathic thrombocytopenic purpura","subitem_subject_scheme":"Other"},{"subitem_subject":"chronic thyroiditis","subitem_subject_scheme":"Other"},{"subitem_subject":"immunoglobulin G","subitem_subject_scheme":"Other"},{"subitem_subject":"platelet-associated immunoglobulin G","subitem_subject_scheme":"Other"},{"subitem_subject":"prednisolone","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"A Case of Autoimmune Hepatitis Associated with Idiopathic Thrombocytopenic Purpura and Chronic Thyroiditis","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"A Case of Autoimmune Hepatitis Associated with Idiopathic Thrombocytopenic Purpura and Chronic Thyroiditis"}]},"item_type_id":"3","owner":"2","path":["30"],"pubdate":{"attribute_name":"公開日","attribute_value":"2008-03-13"},"publish_date":"2008-03-13","publish_status":"0","recid":"20318","relation_version_is_last":true,"title":["A Case of Autoimmune Hepatitis Associated with Idiopathic Thrombocytopenic Purpura and Chronic Thyroiditis"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T02:40:35.239624+00:00"}