{"created":"2023-05-15T16:44:55.201167+00:00","id":20756,"links":{},"metadata":{"_buckets":{"deposit":"6715fe4e-c183-4105-aeb8-f65962992201"},"_deposit":{"created_by":2,"id":"20756","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"20756"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00020756","sets":["35:36"]},"author_link":["87459","87461","87460","87458"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1997-10-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"10","bibliographicPageEnd":"963","bibliographicPageStart":"961","bibliographicVolumeNumber":"59","bibliographic_titles":[{"bibliographic_title":"The journal of veterinary medical science"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"ラット腹腔内にジエチルカルバマジン (DEC, 200mg/kg) を投与後, 血漿中のDEC濃度をガスクロマトグラフィーにて測定し, 血中ミクロフィラリア (mf) 数の変化との相関を調べた. ラットはDEC投与の1日前にB. pahangiのmf, 2×10^5隻を移入し, 人工的にmf血症状態にしておいた. DEC投与後, 30分から4時間の間, 血中のmf数は急激かつ有意に減少し, その後徐々に増加した. DECはラットにおいてB. pahangiのmf血症を一時的にではあるが直接的に抑制することができると考えられる.","subitem_description_type":"Abstract"},{"subitem_description":"Plasma level of diethylcarbamazine (DEC) was measured by using gas chromatography and was compared to the changes of microfilaremia after an intraperitoneal injection with 200mg/kg of DEC in rats. The microfilaremia was induced artificially by an intravenous implantation with 2×10^5 Brugia pahangi microfilariae (mf) 1 day before DEC treatment. The rats treated with DEC showed a rapid and significant decrease in mf number in the circulation within 30 min, continued for 4hr, and then increased rapidly. DEC seemed to cause transsient but significant suppression of microfilaremia of B. pahangi in rats directly.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"The journal of veterinary medical science. 1997, 59(10), p.961-963","subitem_description_type":"Other"}]},"item_2_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"87460","nameIdentifierScheme":"WEKO"}],"names":[{"name":"堀井, 洋一郎"}]},{"nameIdentifiers":[{"nameIdentifier":"87461","nameIdentifierScheme":"WEKO"}],"names":[{"name":"青木, 克己"}]}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"社団法人日本獣医学会"}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"社団法人日本獣医学会"},{"subitem_rights":"本文データは学協会の許諾に基づきCiNiiから複製したものである"}]},"item_2_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA10796138","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"09167250","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Horii, Yoichiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Aoki, Yoshiki"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-23"}],"displaytype":"detail","filename":"JVM59_10_961.pdf","filesize":[{"value":"250.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"JVM59_10_961.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/20756/files/JVM59_10_961.pdf"},"version_id":"f7364672-1517-43be-8577-fa343a6f6f0d"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Brugia pahangi","subitem_subject_scheme":"Other"},{"subitem_subject":"diethylcarbamazine (DEC)","subitem_subject_scheme":"Other"},{"subitem_subject":"microfilaremia.","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Plasma Levels of Diethylcarbamazine and Their Effects on Implanted Microfilariae of Brugia pahangi in Rats","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Plasma Levels of Diethylcarbamazine and Their Effects on Implanted Microfilariae of Brugia pahangi in Rats"}]},"item_type_id":"2","owner":"2","path":["36"],"pubdate":{"attribute_name":"公開日","attribute_value":"2008-04-28"},"publish_date":"2008-04-28","publish_status":"0","recid":"20756","relation_version_is_last":true,"title":["Plasma Levels of Diethylcarbamazine and Their Effects on Implanted Microfilariae of Brugia pahangi in Rats"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T02:22:28.116943+00:00"}