@article{oai:nagasaki-u.repo.nii.ac.jp:00002147,
 author = {Motokucho, Suguru and Morikawa, Hiroshi and Nakatani, Hisayuki and Noordover, Bart A.J.},
 issue = {42},
 journal = {Tetrahedron Letters},
 month = {Oct},
 note = {To develop reaction systems of chemical conversion of biomass, fructose was heated in an aqueous medium under pressurized CO2, which caused in situ generation of carbonic acid. It gave 5-hydroxymethyl-2-furfural (HMF) as a dehydration product in good yields. The maximum yield of HMF was 92% in the reaction at 90 °C under 7.0 MPa of CO2 for 168 h. The reaction proceeded in the absence of any other reagents such as non-volatile acids, organic solvents, inorganic, and organic salts. It means green, environmental-friendly, and efficient process was achieved for production of HMF., Tetrahedron Letters, 57(42), pp.4742-4745; 2016},
 pages = {4742--4745},
 title = {Efficient and environmental-friendly dehydration of fructose to 5-hydroxymethyl-2-furfural in water under high pressure of CO2},
 volume = {57},
 year = {2016}
}