@article{oai:nagasaki-u.repo.nii.ac.jp:00002153, author = {Mohamed, Malik Suliman and Maki, Toshihide and Shah, Mohammad Monir and Ichinose, Yoshio}, issue = {11}, journal = {Biological & Pharmaceutical Bulletin}, month = {Nov}, note = {Two hydroquinone derivatives were prepared and their antimicrobial activity evaluated. Their minimum inhibitory concentrations (MICs) were determined using a broth dilution method. Gentamycin and ciprofloxacin were used as reference antibiotics. The antimicrobial activity of 4-(benzyloxy)phenol (monobenzone) was also evaluated based on its structural similarity to the new compounds; activity was comparable to that of 3,5-dimethyl-4-((4-nitrobenzyl)oxy)phenol (4a). 2,3,5-Trimethyl-4-((4-nitrobenzyl)oxy)phenol (4b) exhibited the best antibacterial activity against both clinical isolates and type strain of Moraxella catarrhalis (M. catarrhalis), with a MIC value of 11 μM, comparable to ciprofloxacin 9 μM., Biological & Pharmaceutical Bulletin, 39(11), pp.1888-1892; 2016}, pages = {1888--1892}, title = {Synthesis and Antimicrobial Activity of Nitrobenzyl-oxy-phenol Derivatives}, volume = {39}, year = {2016} }