@article{oai:nagasaki-u.repo.nii.ac.jp:00002156,
 author = {Takeoka, Atsushi and Tayama, Jun and Yamasaki, Hironori and Kobayashi, Masakazu and Ogawa, Sayaka and Saigo, Tatsuo and Kawano, Hiroaki and Abiru, Norio and Hayashida, Masaki and Maeda, Takahiro and Shirabe, Susumu},
 issue = {45},
 journal = {Medicine},
 month = {Nov},
 note = {Accumulation of intra-abdominal fat is related to hypertension. Despite this, a relationship between hypertension and intra-abdominal fat in young adulthood is not clear. In this study, we verify whether intra-abdominal fat accumulation increases a hypertension risk in young adult subjects. In a cross-sectional study, intra-abdominal fat area was measured using a dual bioelectrical impedance analysis instrument in 697 university students (20.3±0.7 years, 425 men). Blood pressure and anthropometric factors were measured. Lifestyle variables including smoking, drinking, physical activity, and eating behavior were assessed with questionnaire. High blood pressure risk (systolic blood pressure ?130mm Hg and/or diastolic blood pressure ?85mm Hg) with increasing intra-abdominal fat area was evaluated. Participants were divided into 5 groups according to their intra-abdominal fat area (?24.9, 25-49.9, 50-74.9, 75-99.9, and ?100 cm2). As compared with the values of the smallest intra-abdominal fat area group, the crude and lifestyle-adjusted odds ratios (ORs) were elevated in larger intra-abdominal fat area groups [OR 1.31, 95% confidence interval (CI) 0.66-2.80; OR 3.38, 95% CI 1.60-7.57; OR 7.71, 95% CI 2.75-22.22; OR 18.74, 95% CI 3.93-105.64, respectively). The risk increase was observed only in men. Intra-abdominal fat accumulation is related to high blood pressure in men around 20 years of age. These results indicate the importance of evaluation and reduction of intra-abdominal fat to prevent hypertension., Medicine, 95(45),  e5361; 2016},
 title = {Intra-abdominal fat accumulation is a hypertension risk factor in young adulthood: A cross-sectional study},
 volume = {95},
 year = {2016}
}