@article{oai:nagasaki-u.repo.nii.ac.jp:00002170, author = {Mizuta, Satoshi and Otaki, Hiroki and Kitamura, Kanami and Nishi, Kodai and Watanabe, Ken and Makau, Juliann Nzembi and Hashimoto, Ryo and Usui, Toshiya and Chiba, Kenya}, issue = {12}, journal = {Organic Chemistry Frontiers}, month = {Dec}, note = {We herein describe a method for synthetic routes to multi-functionalized-α-trifluoromethyl α,β-unsaturated lactones and trifluoromethyl pyrazolinones. This involves a tandem stereoselective functionalization of 3,3-dibromo-2-trifluoromethyl acrylic acid ethyl ester and intramolecular cyclization reaction to afford precursors for a Suzuki-Miyaura cross-coupling reaction with arylboronic acids., Organic Chemistry Frontiers, 3(12), pp.1661-1667; 2016}, pages = {1661--1667}, title = {3,3-Dibromo-2-trifluoromethyl acrylic acid ethyl ester: a versatile platform for the stereoselective preparation of functionalized-α-trifluoromethyl α,β-unsaturated lactones and trifluoromethyl pyrazolinones}, volume = {3}, year = {2016} }