@article{oai:nagasaki-u.repo.nii.ac.jp:00021754, author = {Shimizu, Kazuhiro}, issue = {1-4}, journal = {Acta medica Nagasakiensia}, month = {Oct}, note = {Emotional stress in rats was induced by "stick-poking harassment" carried out over lengthy periods of 3 months and 1 year, and experimental hypertension was produced. Electron microscopic examination of the adrenal zona fasciculata cells in the experimental group revealed a significant enlargement of the mitochondrion and an increase in the number of lipid droplets in the 3-month group, and a significant enlargement of the mitochondrion in the 1-year group. The plasma corticosterone levels, which were measured at the same time, were significantly higher in the 3-month experimental group, but there was no significant difference noticed in the 1-year group. Corticosterone is a hypertensinogenic steroid, and its involvement in the hypertension was conjectured., Acta medica Nagasakiensia. 1984, 29(1-4), p.40-52}, pages = {40--52}, title = {Experimental Hypertension by Long-Term Emotional Stress and Changes of Adrenal Cortex Morphological and Morphometrical Study}, volume = {29}, year = {1984} }