@article{oai:nagasaki-u.repo.nii.ac.jp:00021775,
 author = {Iseki, Masachika},
 issue = {1-3},
 journal = {Acta medica Nagasakiensia},
 month = {Oct},
 note = {Stress-induced hypertension was produced in rats by exposure to 4±1 °C temperature from one month of age for one hour everyday over several months. Subsequently, significant changes of the cardiovascular system were observed in cold-stress rats. The present experiment used Sprague-Dawley rats (SD rats) and Wistar rats (W rats). There were a few differences between the two. In SD rats, angionecrosis of the coronary artery, fibromuscular sclerosis of the myocardial artery and PN-like lesion in the heart, kidneys and mesentery were observed. In W rats myocardial cell degeneration, fibrosis and mononuclear cell infiltra ion were detected and when compared to non-stress rats there was significant medial thickening of the myocardial artery under 100μm in stressed rats. The implications of exposure to cold in the analysis of cardiovascular pathology accompanied by stress-induced hypertension are discussed., Acta medica Nagasakiensia. 1985, 30(1-3), p.168-179},
 pages = {168--179},
 title = {Experimental Hypertension by Long-Term Cold Stress and Changes of Cardiovascular System},
 volume = {30},
 year = {1985}
}