@article{oai:nagasaki-u.repo.nii.ac.jp:00021842, author = {Shimoyama, Takatoshi and Fukuda, Yutaka and Takahira, Ryohji and Miyashita, Kohsei and Ishikawa, Hiroshi and Tohchika, Hironobu and Yokota, Mitoshi and Kusano, Hiroyuki and Shimizu, Teruhisa and Nakagoe, Tohru and Hirano, Tatsuo and Miura, Toshio and Tomita, Masao}, issue = {1-4}, journal = {Acta medica Nagasakiensia}, month = {Oct}, note = {In order to evaluate the factors affecting the patient's survival, 32 patients of hepatic resection in which the liver had a sollitary hepatocellular carcinoma (HCC) smaller than 5 cm in size were studied. 1) Chronic liver diseases were associated in 96.9 % of patients. Minor resection was done in 30 patients, and right hepatectomy in two. 2) 87.5 % of all cases were diagnosed during periodic follow-up examination for the patients with chronic liver disease, mostly cirrhosis. For small HCC, ultrasonography (US) had the highest detection rate (90%) compared with CT (66.7%) and angiography (55.6%). Preoperative serum AFP values were abnormal in 73%. 3) Grossly, all tumors were nodular or expanding and none was diffuse. Encapsulation appeared to be complete as tumor grew. Portal vein tumor thrombus (12.5%) and/or satellite tumor (31.2%) were frequent in those with larger than 2 cm in diameter. 4) The mortality rate was 9.4% and the hospital mortality rate was 6.3 %. The survival rate of the group with small HCC was far better than that of the groups with HCC larger than 2 cm in size (p<0.05 ). Above findings indicate that early detection of the tumor without portal vein thrombus and/or satellite tumor, and an adequate hepatic resection such as subsegmentectomy or segmentectomy are most improtant for the patient's survival., Acta medica Nagasakiensia. 1988, 33(1-4), p.228-234}, pages = {228--234}, title = {Clinicopathological Study of Hepatocellular Carcinoma in Relation to Tumor Size}, volume = {33}, year = {1988} }