@article{oai:nagasaki-u.repo.nii.ac.jp:00021888,
 author = {Ayabe, Hiroyoshi and Tomita, Masao and Kawahara, Katsunobu and Kimuno, Kouji and Hsieh, Chia-Ming and Oka, Tadayuki and Tsuji, Hiroharu and Nakasone, Tomonori and Taniguchi, Hideki and Touchika, Hironobu and Yasutake, Touru and Okada, Daikichi},
 issue = {2-4},
 journal = {Acta medica Nagasakiensia},
 month = {Dec},
 note = {The surgical specimens obtained from 39 cases in which primary lung cancers were situated in the central portion proximal to subsegmental bronchi were histologically examined as to how long cancer lesions extend along the bronchial wall, based on grossly visible lesions in the mucosa. Of 34 cases, 87% showed proximal cancer extension along the bronchial wall. The mode of cancer spread was mainly adventitioal extension and the distence was within 20mm of the sites of grossly visible lesions in the mucosa. In cases with involvement of the mediastinal lymph nodes and/or carcinoma of undifferentiated histological type, there was a tendency to spread widely. When cancer was located in the orifice of the lobar bronchus, the peripheral cancer spreading was obvious. Based on these results, it is concluded that the site of resection of the bronchus should be 20mm distant from macroscopically recognizable cancer changes in the mucosa. In most cases (71.4%), however the extent of invasion in the bronchial wall was less than 10mm from such changes., Acta medica Nagasakiensia. 1989, 34(2-4), p.234-239},
 pages = {234--239},
 title = {Histological evaluation of cancer extension along the bronchial wall in lung cancer.},
 volume = {34},
 year = {1989}
}