@article{oai:nagasaki-u.repo.nii.ac.jp:00021898, author = {Kose, Noriyuki and Matsuo, Takeshi and Ikeda, Takayoshi and Sohda, Masanori and Shimamine, Ryosuke and Imanishi, Takeo}, issue = {1-4}, journal = {Acta medica Nagasakiensia}, month = {Dec}, note = {Summary : An autopsy case of a 58-year-old female with biliary cystadenocarcinoma is presented. A large cyst occupied the entire left lobe of the liver associating with multilocular daughter cysts and solid lesion. Histologically, tumor showed papillary, back-to-back glandular, cribriform pattern in the inner surface of the cysts with stromal invasion. Polygonal atypical cells were arranged in cords and adenoid cystic pattern in the solid lesion. Immunohistochemically, EMA was stained in the tumor cells as well as normal hepatocytes. CEA was diffusely stained in the cytoplasm and luminar surfaces of the tumor cells, while CEA was stained only in the luminar surfaces of benign-appearing eptithelial cells of the cysts. Keratin and α-fetoprotein were not stained in the tumor cells. The origin of this tumor remains unknown, although transformation from congenital solitary cyst, biliary cystadenoma and reminiscence of cystadenoma of the pancreas or originally occurrence of cystadenocarcinoma in the liver are considered the basic histogenesis of cytadenocarcinoma of this case., Acta medica Nagasakiensia. 1990, 35(1-4), p.10-16}, pages = {10--16}, title = {An Autopsy Case of Biliary Cystadenocarcinoma of the Liver}, volume = {35}, year = {1990} }