@article{oai:nagasaki-u.repo.nii.ac.jp:00021917, author = {Oshibuchi, Tohru}, issue = {1-4}, journal = {Acta medica Nagasakiensia}, month = {Dec}, note = {During the past 14 years, 104 patients received operations for chronic pancreatitis, in the 2nd Department of Surgery, Nagasaki University School of Medicine, in which, there were two cases of lipomatosis of the tail of the pancreas. Angiographical diagnosis revealed the complete devisualization of that area in the phase of the pancreatic parenchyma. It was suggested that reduction of the blood flow into the pancreas brought these pathological changes. Destruction of pancreatic tissues, stricture of the pancreatic duct and fibrosis of the pancreatic parenchyma are well-known as histological findings of chronic pancreatitis, although proliferation of fat tissues in the pancreas is another inevitable finding of chronic pancreatitis. In order to clarify the relationship between arterial circulation and fat replacement of the pancreas, the author carried out the experiments, such as, the arterial ligation, venous ligation, and ligation of both the artery of the pancreas and the pancreatic duct of the canine, respectively. In the arterial ligation group, proliferation of the fatty tissues was observed around 4 weeks after ligation. These experiments showed that disturbance of the blood flow in the pancreatic arteries mainly related to proliferation of fat tissues in the pancreas., Acta medica Nagasakiensia. 1990, 35(1-4), p.103-109}, pages = {103--109}, title = {Etiology of Fat Replacement of the Pancreas}, volume = {35}, year = {1990} }