@article{oai:nagasaki-u.repo.nii.ac.jp:00021918,
 author = {Taniguchi, Hideki and Kawahara, Katsunobu and Nakasone, Tomonori and Ikari, Hideki and Honjoh, Seiji and Hisano, Hiroshi and Takahashi, Takao and Kusano, Hiroyuki and Ayabe, Hiroyoshi and Tomita, Masao},
 issue = {1-4},
 journal = {Acta medica Nagasakiensia},
 month = {Dec},
 note = {This study was performed to clarify the roles of reduced glutathion (GSH), superoxide dismutase (SOD), and solcosaryl in ischemic damage and reperfusion injury to the warm ischemic lungs of experimental animals. Fifty-one warm ischemic canine lungs were made by hilar stripping and clamping of the left PA, PV and bronchus for 2-3 hours. In the Non-perfusion group, GSH (50mg/ kg, I. V.: Group II) and solcoseryl (50mg/kg, I. V.: Group III) were administered. In the perfusion group, Euro-Collins (E-C) solution (20ml/kg) was perfused (Group IV) and GSH (1mg/ml in E-C solution: Group V) and SOD (15mg/l in E-C solution : Group VI) were used for anti-oxidative drugs. The pulmonary arterial pressure and aortic pressure were measured and also blood gas analysis was made during the preischemic period , immediately after, one hour and 3 days after reperfusion. Small parts of pulmonary tissues were taken for pathological examination one hour and 3 days after reperfusion. Chest X-ray films were teken at 3 days after the operation. GSH, SOD, and solcoseryl effectively act as scavengers of active oxygen species (AOS) , especially in terms of oxygenation. In the group with anti-oxidative drugs, cytoprotective effects of the pathological and chest X-ray findings on ischemic damage and reperfusion injury were much more manifest rather than those in control groups., Acta medica Nagasakiensia. 1990, 35(1-4), p.110-115},
 pages = {110--115},
 title = {Cytoprotective roles of GSH, SOD and solcoseryl against ischemic damage and reperfusion injury to warm ischemic lung. Study of Canine warm ischemic lung.},
 volume = {35},
 year = {1990}
}