@article{oai:nagasaki-u.repo.nii.ac.jp:00021960, author = {Tomita, Masao and Nakagoe, Toru and Hirano, Tatsuo and Shimizu, Teruhisa and Kusano, Hiroyuki}, issue = {1-4}, journal = {Acta medica Nagasakiensia}, month = {Dec}, note = {On the basis of a result of clinical experience with the treatment for patients with anal canal cancer, a clinicopathological study of anal canal cancer was performed in comparison with that of colon cancer. Anal canal cancer has a complex histologic types and a tendency toward deep invasion outside the adventitia when compared with colon cancer. Therefore, nodal involvement was in proportion to the depth of cancer infiltration. As a result, the survival time had become worst in patients with Dukes C of anal canal cancer. The anal canal has been defined that as a canal from the level of the attachment of puborectal muscle to the anal verge. It is mainly covered with smooth striated squamous epithelia except for the upper portion which is covered with specialized columnar epithelia, lasting to the rectal epithelium. The structure of the anal canal is complex with the composition of ecto-and endodermal tissues. Anal canal cancer is particular in gross appearance, histologic types and the modes of cancer extension in comparison with rectal cancer. This study defined the clinicopathological specificity of anal canal cancer on the basis of our clinical experience., Acta medica Nagasakiensia. 1991, 36(1-4), p.42-46}, pages = {42--46}, title = {Clinicopathological Study of Anal Canal Cancer}, volume = {36}, year = {1991} }