@article{oai:nagasaki-u.repo.nii.ac.jp:00022001, author = {Senba, Masachika and Zhong, Xue-Yun and Itakura, Hideyo and Matsuo, Takeshi}, issue = {2-4}, journal = {Acta medica Nagasakiensia}, month = {Dec}, note = {Goodpasture's syndrome is characterized by pulmonary associated with renal abnormalities and a group of systemic diseases share immunopathogenic mechanisms which is an autoimmune antiglomerular basement membrane disease. Pulmonary renal syndrome is rather common in the western countries, but rare in Japan. The present two cases showed clinical and pathological features of rapidly progressive glomerulonephritis complicated with massive pulmonary hemorrhage. Most of the hemorrhage appeared acute with intact red blood cells in alveolar spaces, and also had variable numbers of hemosiderin-laden macrophages as an evidence of old hemorrhage. In one case of Goodpasture's syndrome, linear deposits of IgG were demonstrated in alveolar walls, glomerular capillary, Bowman's capsular basement membrane, and tubules of kidneys. These evidences indicate the present two cases to be the so-called Goodpasture's syndrome., Acta medica Nagasakiensia. 1993, 38(2-4), p.49-53}, pages = {49--53}, title = {Alveolar Hemorrhage Associated with Glomerulonephritis So-called Pulmonary Renal (Goodpasture's) Syndrome}, volume = {38}, year = {1993} }