{"created":"2023-05-15T16:45:51.820526+00:00","id":22025,"links":{},"metadata":{"_buckets":{"deposit":"275b0f42-0338-4a5d-81bb-89182b7464a0"},"_deposit":{"created_by":2,"id":"22025","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"22025"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00022025","sets":["29:30:1713167819629:1563"]},"author_link":["93999","94001","94002","94003","94000"],"item_3_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1993-12-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2-4","bibliographicPageEnd":"167","bibliographicPageStart":"164","bibliographicVolumeNumber":"38","bibliographic_titles":[{"bibliographic_title":"Acta medica Nagasakiensia"}]}]},"item_3_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"It is difficult to propose simple idea in which cell adhesion molecules can he related to tumor growth and metastasis. The integrins function as extracellular matrix receptors binding to such proteins as collagen, laminin, and fibronectin. In this study, the cell culture of human glioma cells were xenografted to nude mice and rats associated with laminin injection, resulting in tumor growth and metastasis in the large amount of laminin group. In nude mouse experiment, cultured glioma cells were xenografted in the back of cutaneous with 10μg and 100μg laminin. The tumor lump of the 100μg laminin group grew faster and larger than the 10μg laminin group. In nude rat experiment, cultured glioma cells were xenografted intravascularly in the tail with l0μg and 100μg laminin. Of the 6 cases, 4 (66.7%) showed metastasis in the lungs after 2 weeks in the 100μg laminin group. However, metastasis was not detected in 10μg laminin group. These results suggest that quantities of laminin may play an important role in tumor growth and metastasis.","subitem_description_type":"Abstract"}]},"item_3_description_64":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Acta medica Nagasakiensia. 1993, 38(2-4), p.164-167","subitem_description_type":"Other"}]},"item_3_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00508430","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00016055","subitem_source_identifier_type":"ISSN"}]},"item_3_text_62":{"attribute_name":"sortkey","attribute_value_mlt":[{"subitem_text_value":"P00164-P00167"}]},"item_3_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Zhong, Xue-Yun"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Senba, Masachika"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Chen, Yun-Xian"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nishigami, Takashi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Miyaji, Hideki"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-23"}],"displaytype":"detail","filename":"acta38_02_27_t.pdf","filesize":[{"value":"619.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"acta38_02_27_t.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/22025/files/acta38_02_27_t.pdf"},"version_id":"93dd5268-9fe3-46e7-b5a9-a9b139372164"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"The Role of Laminin on Cultured Human Glioma Cell Proliferation and Metastasis in Nude Mice and Rats","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"The Role of Laminin on Cultured Human Glioma Cell Proliferation and Metastasis in Nude Mice and Rats"}]},"item_type_id":"3","owner":"2","path":["1563"],"pubdate":{"attribute_name":"公開日","attribute_value":"2008-03-13"},"publish_date":"2008-03-13","publish_status":"0","recid":"22025","relation_version_is_last":true,"title":["The Role of Laminin on Cultured Human Glioma Cell Proliferation and Metastasis in Nude Mice and Rats"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2024-04-17T04:07:46.688337+00:00"}