{"created":"2023-05-15T16:45:52.917057+00:00","id":22042,"links":{},"metadata":{"_buckets":{"deposit":"794eb896-f815-402e-8c57-2391cb300d57"},"_deposit":{"created_by":2,"id":"22042","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"22042"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00022042","sets":["29:30:1713167819629:1563"]},"author_link":["94104","94103","94102"],"item_3_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1993-12-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2-4","bibliographicPageEnd":"246","bibliographicPageStart":"242","bibliographicVolumeNumber":"38","bibliographic_titles":[{"bibliographic_title":"Acta medica Nagasakiensia"}]}]},"item_3_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Histopathological analysis was carried out to examine the characteristics of nasopharyngeal carcinoma (NPC) using 38 biopsy cases obtained from southern China and 34 cases obtained from Japan. These cases were divided into three groups according to their predominant pattern associated with the cell and the tissue differentiation using the World Health Organization (WHO) histological classification of tumors as follows: (i) squamous cell carcinoma; 6 Chinese cases and 5 Japanese cases, (ii) differentiated nonkeratinizing carcinoma; 25 Chinese cases and 7 Japanese cases, (iii) undifferentiated carcinoma; 7 Chinese cases and 22 Japanese cases. The age of Chinese patients ranged from 21 to 80 years with a mean of 46 years and Japanese patients ranged from 17 to 89 years with a mean of 53.8 years. The male to female ratio was 2.7:1.0 in China and 1.8:1.0 in Japan. The most common histological type of NPC in China was differentiated non-keratinizing carcinoma, however, it was undifferentiated carcinoma in Japan. The mechanism of cancer arising from the nasopharynx may be quite different between Chinese and Japanese cases. The Chinese NPC cases were considered as continuity shift from normal epithelium to differentiated nonkeratinizing carcinoma, to undifferentiated carcinoma sequence. On the other hand, the Japanese cases were considered discontinuity shift. Therefore, in Chinese cases, NPC formation mechanism may be that EBV infection and chemical carcinogens can act synergistically in the enhancement of both viral replication and malignant transformation. It is suggested that some Japanese cases are associated with Epstein- Barr virus infection, although, mechanism of formation of NPC in Japanese cases is not yet clear.","subitem_description_type":"Abstract"}]},"item_3_description_64":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Acta medica Nagasakiensia. 1993, 38(2-4), p.242-246","subitem_description_type":"Other"}]},"item_3_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00508430","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00016055","subitem_source_identifier_type":"ISSN"}]},"item_3_text_62":{"attribute_name":"sortkey","attribute_value_mlt":[{"subitem_text_value":"P00242-P00246"}]},"item_3_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Senba, Masachika"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Zhong, Xue-Yun"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Itakura, Hideyo"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-23"}],"displaytype":"detail","filename":"acta38_02_44_t.pdf","filesize":[{"value":"1.1 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"acta38_02_44_t.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/22042/files/acta38_02_44_t.pdf"},"version_id":"bffa9659-4c46-4694-817e-7ecabc26d631"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Histopathological Difference of Nasopharyngeal Carcinoma in Southern China and Japan","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Histopathological Difference of Nasopharyngeal Carcinoma in Southern China and Japan"}]},"item_type_id":"3","owner":"2","path":["1563"],"pubdate":{"attribute_name":"公開日","attribute_value":"2008-03-13"},"publish_date":"2008-03-13","publish_status":"0","recid":"22042","relation_version_is_last":true,"title":["Histopathological Difference of Nasopharyngeal Carcinoma in Southern China and Japan"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2024-04-17T04:07:50.274839+00:00"}