@article{oai:nagasaki-u.repo.nii.ac.jp:00022048, author = {Tomita, Masao and Hara, Shinsuke and Tagawa, Yutaka and Kawahara, Katsunobu and Ayabe, Hiroyoshi and Obatake, Masayuki and Sawai, Terumitsu and Jibiki, Masaaki and Morinaga, Masafumi and Matsuo, Toshikazu and Matsuo, Satoshi and Yoshida, Akira and Furukawa, Taizou and Yoshida, Ryuichiro and Eguchi, Masaaki and Takahashi, Takao and Sakai, Tsutomu and Okada, Daikichi and Makiyama, Takao}, issue = {2-4}, journal = {Acta medica Nagasakiensia}, month = {Dec}, note = {Surgical outcome for advanced esophageal cancer patients is not satisfactory in spite of improvements of diagnostic tools, operative techniques, postoperative cares and adjuvant chemotherapy. Postoperative prognosis used to be predicted by the grades of histologic disease progression. However, it is limited to accurate prediction of its prognosis. Recent studies have been focused on biologic behavior of malignant cells, in particular, nuclear DNA contents which play an important role in cell proliferation and metabolizm. Clinical use of flow-cytometric measurement of nuclear DNA is now prevalent to assess the grades of malignancy for malignant tumors. In contrast, it is difficult to know nuclear DNA contents preoperatively. The purpose of this study is to clarify whether or not preoperative biologic behaviors is clinically feasible, from biopsied specimens in comparison with that from the surgical specimens., Acta medica Nagasakiensia. 1993, 38(2-4), p.270-272}, pages = {270--272}, title = {DNA Analysis from Biopsied Specimens for Carcinomas of the Esophagus}, volume = {38}, year = {1993} }