@article{oai:nagasaki-u.repo.nii.ac.jp:00022057, author = {Liu, Zhi and Imamura, Toshiyuki and Miyahara, Yoshiyuki and Hara, Kohei}, issue = {1-3}, journal = {Acta medica Nagasakiensia}, month = {Oct}, note = {The present study was undertaken to assess the cardiopulmonary response during the initial period of exercise at a low workload in 8 patients with COPD and 10 normal subjects. In the patients with COPD VO2/VE and VCO2/VE were significantly lower than in the normal controls, and more markedly so during the initial period of exercise. SaO2 and Sv O2 decreased dramatically in the initial period of exercise in the COPD compared with the normal subjects. In contrast to the normal subjects, pulmonary artery mean pressure (PAMP) increased substantially during the initial period of exercise in the patients with COPD. These findings imply that blood gas changes on exercise can be explained by the differences in the relative increase of VO2, VCO2, VE and cardiac output. Our study also suggests that the measurement of VO2/VE, VCO2/VE and SvO2 and PAMP on exercise at a low workload, especially during the initial period, may be useful for evaluating the cardiopulmonary response to COPD patients., Acta medica Nagasakiensia. 1994, 39(1-3), p.1-4}, pages = {1--4}, title = {Initial Cardiopulmonary Response to Exercise in Chronic Obstructive Pulmonary Diseases (COPD)}, volume = {39}, year = {1994} }