@article{oai:nagasaki-u.repo.nii.ac.jp:00023155,
 author = {Nagae, Masaki and Shiroyama, Ken'Ichirou and Inoue, Mihoka and Hara, Akihiko and Takao, Yuji and Kohra, Shinya and Ishibashi, Yasuhiro and Tominaga, Nobuaki and Yoshihara, Shin'Ichi and Arizono, Koji},
 issue = {1},
 journal = {Journal of Health Science},
 month = {Feb},
 note = {We investigated the estrogenic activity of a bisphenol A (BPA) metabolite (4-methyl-2,4-bis(p-hydroxyphenyl)-pent-1-ene; MBP) in male medaka (Oryzias latipes) using vitellogenin (Vg, Vg1 and Vg2) as a biomarker. Male d-rR medaka were exposed to various concentrations of estradiol-17β (E2), MBP and BPA for 3 days, and then the serum Vg concentration was measured using specific chemiluminescent immunoassays. The estimated relative estrogenic activities of MBP and BPA compared with E2 (100%) were 1.3-1.4% and 0.00010-0.00023%, respectively. These findings indicated that MBP has about 104-fold higher estrogenic potency than the parent BPA and about 1/50 that of E2 for Vg synthesis in medaka. This is the first study to show that MBP can act as a highly potent estrogen agonist in living organisms., Journal of Health Science v.51(1) p.93-95, 2005},
 pages = {93--95},
 title = {Estrogenic Potency of a Bisphenol A Metabolite on Vitellogenin Synthesis in Medaka, Oryzias latipes},
 volume = {51},
 year = {2005}
}