{"created":"2023-05-15T16:31:02.821044+00:00","id":2346,"links":{},"metadata":{"_buckets":{"deposit":"f7c07acd-dad6-40dd-8eeb-c12375f2f272"},"_deposit":{"created_by":2,"id":"2346","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"2346"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00002346","sets":["8:9"]},"author_link":["10906","10903","10905","10908","10899","10904","10901","10911","10907","10909","10900","10912","10910","10902"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-03-26","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"1470","bibliographicPageStart":"1464","bibliographicVolumeNumber":"23","bibliographic_titles":[{"bibliographic_title":"Medical Science Monitor"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background: Endocan is expressed in vascular endothelial cells, and its expression is enhanced following endothelial injury via inflammatory cytokines. Subsequently, endocan is secreted into the circulation. Thus, serum endocan levels are considered a marker of endothelial injury. However, to the best of our knowledge, no data on the serum endocan levels in peritoneal dialysis (PD) patients are available. Material/Methods: This study included 21 PD patients who underwent peritoneal equilibration test (PET) more than once between 2011 and 2015. Serum samples were collected from each patient, and the 24-h urine volume was measured at the time of PET. Serum endocan levels were measured using enzyme-linked immunosorbent assay (ELISA) at the time of the first PET, and their relationship with clinical data or the extent of urine volume decline (mL/year) was analyzed retrospectively. Results: Serum endocan levels were positively correlated with proteinuria level, serum creatinine level, serum tumor necrosis factor (TNF)-α level, β2-microglobulin level, and PD drainage volume, but not with urine volume at baseline. The extent of decline in urine volume was significantly associated with serum endocan level, proteinuria level, serum creatinine level, and serum TNF-α level at baseline in a simple linear regression analysis. Moreover, multiple linear regression analysis showed that the serum endocan level and proteinuria level at baseline were independent predictors for the extent of decline in urine volume. Conclusions: The results of this study indicate that serum endocan level and proteinuria level may be useful predictive markers for decreased urine volume in PD patients.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Medical Science Monitor, 23, pp.1464-1470; 2017","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"International Scientific Information"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.12659/MSM.900693","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"c Medical Science Monitor"},{"subitem_rights":"This work is licensed under Creative Common Attribution- NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"}]},"item_2_source_id_8":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"16433750","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Oka, Satoru"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Obata, Yoko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sato, Shuntaro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Torigoe, Kenta"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sawa, Miki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Abe, Shinichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Muta, Kumiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ota, Yuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kitamura, Mineaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kawasaki, Satoko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hirose, Misaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Uramatsu, Tadashi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Mukae, Hiroshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nishino, Tomoya"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-21"}],"displaytype":"detail","filename":"MSM23_1464.pdf","filesize":[{"value":"142.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"MSM23_1464.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/2346/files/MSM23_1464.pdf"},"version_id":"09cddb54-33df-4483-b9fd-da5ec90c1cc1"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Endocan","subitem_subject_scheme":"Other"},{"subitem_subject":"Endothelial injury","subitem_subject_scheme":"Other"},{"subitem_subject":"Peritoneal dialysis","subitem_subject_scheme":"Other"},{"subitem_subject":"Residual renal function","subitem_subject_scheme":"Other"},{"subitem_subject":"Tumor necrosis factor-alpha","subitem_subject_scheme":"Other"},{"subitem_subject":"Urine volume","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Serum Endocan as a Predictive Marker for Decreased Urine Volume in Peritoneal Dialysis Patients","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Serum Endocan as a Predictive Marker for Decreased Urine Volume in Peritoneal Dialysis Patients"}]},"item_type_id":"2","owner":"2","path":["9"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-06-12"},"publish_date":"2017-06-12","publish_status":"0","recid":"2346","relation_version_is_last":true,"title":["Serum Endocan as a Predictive Marker for Decreased Urine Volume in Peritoneal Dialysis Patients"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T03:48:23.547666+00:00"}