@article{oai:nagasaki-u.repo.nii.ac.jp:00024998, author = {TRANGAY, Maria de Lourdes Aracely LUJAN and 坂本, 信 and 嶋田, 雅暁 and 木村, 英作 and 青木, 克己}, issue = {1}, journal = {熱帯医学 Tropical medicine}, month = {Mar}, note = {Dirofilaria immitisミクロフィラリア30,000隻を6匹のICRマウスのソ径部皮下に毎週1回10週間接種後DEC 300mg/kgで3日間治療した.DEC投与前のIHA titerの最高値は1:240であったが投与後1週目よりtiterは上昇し始め4週目には全てのマウスが最高値(4匹は1:960,2匹は1:480)を示し6週までの観察期間ではtiterは最高値を維持した., About 30,000 microfilariae of D. immitis were inoculated into ICR mice subcutaneously. The mice were injected with DEC at 300mg/kg/day for 3 consecutive days, then the IHA test was carried out until 6 weeks after DEC treatment. Before DEC treatment, the IHA titers in two of six mice was 1:240 and those in the other four was 1:120. One week after DEC treatment, the IHA titer began to rise in most mice and at 4 weeks, those in all mice reached maximum. During the observation period, the maximum titers in four of six mice was 1:960 and those in the remaining two was 1:480., 熱帯医学 Tropical medicine 26(1). p11-15, 1984}, pages = {11--15}, title = {Dirofilaria immitisミクロフィラリア感染マウスに於けるDiethylcarbamazine投与時のIHA titerの変動}, volume = {26}, year = {1984} }