{"created":"2023-05-15T16:48:11.721907+00:00","id":25139,"links":{},"metadata":{"_buckets":{"deposit":"213f675c-54b0-46b6-8943-e8766a23f10c"},"_deposit":{"created_by":2,"id":"25139","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"25139"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00025139","sets":["35:1741:1775:1860"]},"author_link":["106744","106748","106743","106741","106742","106740","106745","106746","106749","106747"],"item_3_alternative_title_19":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"A Role of Protease Produced by Vibrio cholerae in Its Adherent Mechanism"}]},"item_3_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1988-03-31","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"38","bibliographicPageStart":"33","bibliographicVolumeNumber":"30","bibliographic_titles":[{"bibliographic_title":"熱帯医学 Tropical medicine"}]}]},"item_3_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"コレラ菌感染における腸管上皮定着性とプロテアーゼ活性との関連を明らかにするためにクラシック型,エルトール型及びnon-O1コレラ菌,各々10,15,10株を用いてプロテアーゼ活性及び成熟ウサギループテストにおける投与後13時間の腸管上皮定着性を検討した.その結果非定着菌群のプロテアーゼ活性は高度定着菌群のそれより高い値を示しその平均値の差は有意であった(T-test, p<0.05)即ち,In vitroでのプロテアーゼ産生量はコレラ菌の小腸上皮における定着の程度とは必ずしも相関しないことが示唆された.","subitem_description_type":"Abstract"},{"subitem_description":"The relationship between protease activity in vitro and the degree of colonization of Vibrio cholerae in the ileal loop test was investigated using 35 strains of V. cholerae (biotype classical, El Tor and non-O1 V. cholerae, 10, 15, and 10 respectively). The mean protease activity in non adherent group was 9.15 mm, higher than that in adherent (+) and (++) group, 6.74mm and 6.19mm, respectively in agar-gel single-diffusion method. The difference between the mean protease activity in non-adherent and adherent (++) groups was statistically significant (T-test, p<0.05). This suggests that the amount of protease produced in vitro does not necessarily correlate with the adherent potential of the vibrios to the intestinal epithelial cells.","subitem_description_type":"Abstract"}]},"item_3_description_64":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"熱帯医学 Tropical medicine 30(1). p33-38, 1988","subitem_description_type":"Other"}]},"item_3_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"106745","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Supawat, Krongkaew"}]},{"nameIdentifiers":[{"nameIdentifier":"106746","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Ichinose, Yoshio"}]},{"nameIdentifiers":[{"nameIdentifier":"106747","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Ishibashi, Mikako"}]},{"nameIdentifiers":[{"nameIdentifier":"106748","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Ehara, Masahiko"}]},{"nameIdentifiers":[{"nameIdentifier":"106749","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Naito, Tatsuro"}]}]},"item_3_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"長崎大学熱帯医学研究所"}]},"item_3_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00199644","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03855643","subitem_source_identifier_type":"ISSN"}]},"item_3_text_62":{"attribute_name":"sortkey","attribute_value_mlt":[{"subitem_text_value":"P00033-P00038"}]},"item_3_text_63":{"attribute_name":"出版者別言語","attribute_value_mlt":[{"subitem_text_value":"Institute of Tropical Medicine, Nagasaki University"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"クロンキャー, ウスパワット"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"一瀬, 休生"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"石橋, 美雅子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"江原, 雅彦"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"内藤, 達郎"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-24"}],"displaytype":"detail","filename":"tm30_01_04_t.pdf","filesize":[{"value":"1.2 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"tm30_01_04_t.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/25139/files/tm30_01_04_t.pdf"},"version_id":"9c631297-8f5f-491c-8240-d69117a58889"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"コレラ菌の定着性とそのプロテアーゼ活性との関連について","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"コレラ菌の定着性とそのプロテアーゼ活性との関連について"}]},"item_type_id":"3","owner":"2","path":["1860"],"pubdate":{"attribute_name":"公開日","attribute_value":"2006-04-26"},"publish_date":"2006-04-26","publish_status":"0","recid":"25139","relation_version_is_last":true,"title":["コレラ菌の定着性とそのプロテアーゼ活性との関連について"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-15T23:48:25.716015+00:00"}