@article{oai:nagasaki-u.repo.nii.ac.jp:00025220,
 author = {Kiyohara, Tatsuo and Watanabe, Masami and Ichinose, Yoshio and Naito, Tatsuro and Nakamura, Michio and Itakura, Hideyo},
 issue = {1},
 journal = {熱帯医学 Tropical medicine},
 month = {Mar},
 note = {Cholera toxin added to an assay mixture significantly inhibited the cytotoxic activity of lymphokine-activated killer (LAK) cells derived from normal human peripheral blood leukocytes (PBLs). LAK cells preincubated with the toxin lost 90% of their cytolytic activity. In vitro activation of killer cells by Interleukin-2 from PBLs was not affected by the toxin. These results indicate that LAK cells are directly impaired of the cytolytic activity by the toxin and that the generation of LAK cells is not inhibited by it. LAK cells from a HIV carrier were more sensitive to the toxin than those from normal controls. Chemotherapy-activated killer (CAK) cells (Kiyohara et al., 1988) which had been activated in vivo were also impaired of the cytotoxic function by the toxin., 熱帯医学 Tropical medicine 34(1). p21-27, 1992},
 pages = {21--27},
 title = {Cytotoxic Activities of Lymphokine-activated Killer Cells and Chemotherapy-activated Killer Cells are Inhibited by Cholera Toxin},
 volume = {34},
 year = {1992}
}