{"created":"2023-05-15T16:48:22.428589+00:00","id":25382,"links":{},"metadata":{"_buckets":{"deposit":"de746c52-5b7f-47c6-b4a5-4241958f3fac"},"_deposit":{"created_by":2,"id":"25382","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"25382"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00025382","sets":["35:1741:1775:1898"]},"author_link":["107692","107696","107695","107693","107694"],"item_3_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1998-10-30","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"97","bibliographicPageStart":"95","bibliographicVolumeNumber":"40","bibliographic_titles":[{"bibliographic_title":"熱帯医学 Tropical medicine"}]}]},"item_3_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"A simple and reproducible screening method of macrofilaricides is described. The method evaluated in the present paper is based on inhibitory activity of the drugs on acid-phosphatase of Dirofilaria immitis adult worms. The potent inhibitor of acid-phosphates, NaF, inhibited completely the enzymic activity at 1 mM. trimelarsan, suramin and flubendazole inhibited partially the enzymic activity. Their inhibitory activity is comparable to that of Na_2HAsO_4, a specific inhibitor of phosphatase. Diethylcarbamazine and levamisole did not inhibit the phosphatase of D. immitis.","subitem_description_type":"Abstract"}]},"item_3_description_64":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"熱帯医学 Tropical medicine 40(2). p95-97, 1998","subitem_description_type":"Other"}]},"item_3_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"長崎大学熱帯医学研究所"}]},"item_3_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00199644","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03855643","subitem_source_identifier_type":"ISSN"}]},"item_3_text_62":{"attribute_name":"sortkey","attribute_value_mlt":[{"subitem_text_value":"P00095-P00097"}]},"item_3_text_63":{"attribute_name":"出版者別言語","attribute_value_mlt":[{"subitem_text_value":"Institute of Tropical Medicine, Nagasaki University"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Maki, Jun"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kuwata, Masahiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Mitsui, Yoshinori"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fujimaki, Yasunori"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ito, Yoichi"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-24"}],"displaytype":"detail","filename":"tm40_02_03_t.pdf","filesize":[{"value":"268.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"tm40_02_03_t.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/25382/files/tm40_02_03_t.pdf"},"version_id":"7b7ee016-89d5-452f-805e-44e2ba1acaa9"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"A Simple Method for Screening of Macrofilaricidal Compounds-The Inhibitory Effect of Substances on Phosphatase Activity of Adult Dirofilaria immitis","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"A Simple Method for Screening of Macrofilaricidal Compounds-The Inhibitory Effect of Substances on Phosphatase Activity of Adult Dirofilaria immitis"}]},"item_type_id":"3","owner":"2","path":["1898"],"pubdate":{"attribute_name":"公開日","attribute_value":"2006-04-26"},"publish_date":"2006-04-26","publish_status":"0","recid":"25382","relation_version_is_last":true,"title":["A Simple Method for Screening of Macrofilaricidal Compounds-The Inhibitory Effect of Substances on Phosphatase Activity of Adult Dirofilaria immitis"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-15T23:38:11.785488+00:00"}