{"created":"2023-05-15T16:49:00.782651+00:00","id":26270,"links":{},"metadata":{"_buckets":{"deposit":"b6dca82d-f0d3-4d2f-a1aa-021f28880307"},"_deposit":{"created_by":6,"id":"26270","owners":[6],"pid":{"revision_id":0,"type":"depid","value":"26270"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00026270","sets":["35:36"]},"author_link":["112277","112276","112274","112273","112271","112278","112275","112272"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-01-04","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageStart":"art.no.2","bibliographicVolumeNumber":"49","bibliographic_titles":[{"bibliographic_title":"Tropical Medicine and Health"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background: Tibetan highlanders have adapted to hypoxic environments through the development of unique mechanisms that suppress an increase in hemoglobin (Hb) concentration even in high-altitude areas. Hb concentrations generally decrease with increasing age. However, in the highlands, chronic altitude sickness is known to occur in the elderly population. To investigate how aging in a hypoxic environment affects Hb levels in Tibetan highlanders, we focused on the Mustang people, who live above 3500 m. We tried to clarify the pure relationship between aging and Hb levels in a hypoxic environment.Results: We found that the Hb concentration increased with increasing age in females but not in males. Multivariate analysis showed that age, pulse pressure, the poverty index, and vascular diameter were strongly correlated with the Hb concentration. Conclusions: We found unique Hb dynamics among female Tibetan highlanders. As seen in these Hb dynamics, there may be sex-based differences in the adaptive mechanism in Tibetan highlanders.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Tropical Medicine and Health, 49(1), art.no.2; 2020","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"BioMed Central Ltd"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1186/s41182-020-00289-6","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2021, The Author(s). Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you giveappropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate ifchanges were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.                                                                                                                                                                                                                                                                                                                                                                                "}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1349-4147","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Arima, Hiroaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakano, Masayuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Koirala, Sweta"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ito, Hiromu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Pandey, Basu Dev"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Pandey, Kishor"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Wada, Takayuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamamoto, Taro"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-01-22"}],"displaytype":"detail","filename":"TMH49_2.pdf","filesize":[{"value":"1.4 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"TMH49_2.pdf ","url":"https://nagasaki-u.repo.nii.ac.jp/record/26270/files/TMH49_2.pdf"},"version_id":"5c564910-1bef-4750-b740-486b1071e823"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Unique hemoglobin dynamics in female Tibetan highlanders","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Unique hemoglobin dynamics in female Tibetan highlanders"}]},"item_type_id":"2","owner":"6","path":["36"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-01-22"},"publish_date":"2021-01-22","publish_status":"0","recid":"26270","relation_version_is_last":true,"title":["Unique hemoglobin dynamics in female Tibetan highlanders"],"weko_creator_id":"6","weko_shared_id":-1},"updated":"2023-05-15T22:55:41.155387+00:00"}