{"created":"2023-05-15T16:49:01.997375+00:00","id":26299,"links":{},"metadata":{"_buckets":{"deposit":"a88307b1-6b49-47f4-a615-58d97b3e1a50"},"_deposit":{"created_by":6,"id":"26299","owners":[6],"pid":{"revision_id":0,"type":"depid","value":"26299"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00026299","sets":["35:36"]},"author_link":["117004","117006","117010","117016","117009","117013","117008","117019","117005","117011","117020","117017","117018","117002","117012","117014","117003","117007","117015"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-01-11","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageStart":"337","bibliographicVolumeNumber":"11","bibliographic_titles":[{"bibliographic_title":"Scientific Reports"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Conjunctival pneumococcal serotypes among members of a community have not been investigated well. We determined the prevalence and association of Streptococcus pneumoniae in the nasopharynx and conjunctiva among children in a community before pneumococcal conjugate vaccine introduction. In October 2016, conjunctival and nasopharyngeal swabs were collected from children (< 24 months old) and nasopharyngeal swabs from mothers in Nha Trang, Vietnam. Quantitative lytA PCR and DNA microarray were performed to detect and serotype S. pneumoniae. The association between S.pneumoniae in the nasopharynx and conjunctiva was evaluated using multivariable logistic regression model. Among 698 children,62 (8.9%, 95% CI 6.9–11.2%) were positive for S. pneumoniae in the conjunctiva. Non-encapsulated S. pneumoniae were most commonly identified,followed by serotypes 6A, 6B, and 14. Nasopharyngeal and conjunctival detection were positively associated (aOR 47.30, 95% CI 24.07–92.97). Low birth-weight, day-care attendance, and recent eye symptoms were independently associated with S. pneumoniae detection in the conjunctiva (aOR 11.14, 95% CI 3.76–32.98, aOR 2.19, 95% CI 1.45–3.31, and aOR 3.59, 95% CI 2.21–5.84, respectively). Serotypes and genotypes in the conjunctiva and nasopharynx matched in 87% of the children. Three mothers’ nasopharyngeal pneumococcal samples had matched serotype and genotype with their child’s in the conjunctiva and nasopharynx. S. pneumoniae presence in nasopharynx and conjunctiva were strongly associated. The high concordance of serotypes suggests nasopharyngeal carriage may be a source of transmission to the conjunctiva.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Scientific Reports, 11(1), art.no.337; 2021","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Nature Research"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1038/s41598-020-79175-4","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2021, The Author(s). Open  Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/."}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2045-2322","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Mohamed, Yasser Helmy"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Toizumi, Michiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Uematsu, Masafumi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nguyen, Hien-Anh Thi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Le, Lien Thuy"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takegata, Mizuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Iwasaki, Chihiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kitamura, Noriko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nation, Monica L."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Dunne, Eileen M."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hinds, Jason"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Do, Hung Thai"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Vien, Mai Quang"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Satzke, Catherine"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Flasche, Stefan"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Mulholland, Kim"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Dang, Duc-Anh"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kitaoka, Takashi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yoshida, Lay-Myint"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-02-03"}],"displaytype":"detail","filename":"SciRep11_337.pdf","filesize":[{"value":"1.8 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"SciRep11_337.pdf ","url":"https://nagasaki-u.repo.nii.ac.jp/record/26299/files/SciRep11_337.pdf"},"version_id":"09b2e89c-65d2-4a55-b4b0-e22abc0fd443"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Prevalence of Streptococcus pneumoniae in conjunctival flora and association with nasopharyngeal carriage among children in a Vietnamese community","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Prevalence of Streptococcus pneumoniae in conjunctival flora and association with nasopharyngeal carriage among children in a Vietnamese community"}]},"item_type_id":"2","owner":"6","path":["36"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-02-03"},"publish_date":"2021-02-03","publish_status":"0","recid":"26299","relation_version_is_last":true,"title":["Prevalence of Streptococcus pneumoniae in conjunctival flora and association with nasopharyngeal carriage among children in a Vietnamese community"],"weko_creator_id":"6","weko_shared_id":-1},"updated":"2023-05-15T20:37:59.835292+00:00"}