@article{oai:nagasaki-u.repo.nii.ac.jp:00026347,
 author = {Kaku, Norihito and Ohnishi, Takamitsu and Matsumoto, Tetsuya and Watanabe, Shinichi and Yanagihara, Katsunori},
 issue = {12},
 journal = {The Journal of Dermatology},
 month = {Dec},
 note = {Skin and soft tissue infections (SSTI) are a common infection among both outpatients and inpatients. The most frequently isolated bacterium in SSTI was Staphylococcus aureus, a quarter of which was methicillin-resistant S. aureus (MRSA). In this study, to investigate molecular epidemiology of the 141 MRSA strains collected in the Japanese nationwide surveillance, we performed multiplex real-time polymerase chain reaction to detect staphylococcal cassette chromosome mec (SCCmec) type and virulence genes. The percentage of SCCmec types I, II, III and IV was 1.4%, 52.5%, 5.7% and 40.4%, respectively. According to the SCCmec type, we classified the strains into health-care-associated (HA)-MRSA (n = 84) and community-associated (CA)-MRSA (n = 57). Among the virulence genes, the percentage of enterotoxin C gene-positive strains was significantly higher in CA-MRSA than in HA-MRSA. No significant differences were detected between the two groups in terms of antibiotic susceptibility and patients’ background information, classification of SSTI or symptoms of SSTI., The Journal of Dermatology, 46(12), pp.1205-1209; 2019},
 pages = {1205--1209},
 title = {Molecular characteristics of methicillin-resistant Staphylococcus aureus isolated from skin and soft tissue infections collected in the Japanese nationwide surveillance},
 volume = {46},
 year = {2019}
}