{"created":"2023-05-15T16:49:23.326406+00:00","id":26823,"links":{},"metadata":{"_buckets":{"deposit":"0cfc51ce-b046-42a1-bab5-083886785bf6"},"_deposit":{"created_by":6,"id":"26823","owners":[6],"pid":{"revision_id":0,"type":"depid","value":"26823"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00026823","sets":["143:144"]},"author_link":["118850","118856","118851","118852","118855","118853","118848","118849","118854"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-05-27","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"art. no. 11117","bibliographicVolumeNumber":"11","bibliographic_titles":[{"bibliographic_title":"Scientific Reports"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Vertebrates usually exhibit gonochorism, whereby their sex is fixed throughout their lifetime. However, approximately 500 species (~ 2%) of extant teleost fishes change sex during their lifetime. Although phylogenetic and evolutionary ecological studies have recently revealed that the extant sequential hermaphroditism in teleost fish is derived from gonochorism, the evolution of this transsexual ability remains unclear. We revealed in a previous study that the tunica of the ovaries of several protogynous hermaphrodite groupers contain functional androgen-producing cells, which were previously unknown structures in the ovaries of gonochoristic fishes. Additionally, we demonstrated that these androgen-producing cells play critical roles in initiating female-to-male sex change in several grouper species. In the present study, we widened the investigation to include 7 genera and 18 species of groupers and revealed that representatives from most major clades of extant groupers commonly contain these androgen-producing cells, termed testicular-inducing steroidogenic (TIS) cells. Our findings suggest that groupers acquired TIS cells in the tunica of the gonads for successful sex change during their evolution. Thus, TIS cells trigger the evolution of sex change in groupers.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Scientific Reports, 11, art. no. 11117; 2021","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Springer Nature"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1038/s41598-021-90691-9","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© The Author(s) 2021. This  article  is  licensed  under  a  Creative  Commons  Attribution  4.0  International   License, which permits use, sharing, adaptation, distribution and reproduction in any medium or  format,  as  long  as  you  give  appropriate  credit  to  the  original  author(s)  and  the  source,  provide  a  link  to  the   Creative Commons licence, and indicate if changes were made. The images or other third party material in this  article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the  material.  If  material  is  not  included  in  the  article’s  Creative  Commons  licence  and  your  intended  use  is  not   permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from  the copyright holder. To view a copy of this licence, visit http:// creat iveco mmons. org/ licen ses/ by/4. 0/."}]},"item_2_source_id_8":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"20452322","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Murata, Ryosuke"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nozu, Ryo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Mushirobira, Yuji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Amagai, Takafumi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fushimi, Jun"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kobayashi, Yasuhisa"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Soyano, Kiyoshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nagahama, Yoshitaka"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakamura, Masaru"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-10-28"}],"displaytype":"detail","filename":"SciRep11_11117.pdf","filesize":[{"value":"2.2 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"SciRep11_11117.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/26823/files/SciRep11_11117.pdf"},"version_id":"750dd05d-a19c-45a0-8f66-7c56869e684b"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Testicular inducing steroidogenic cells trigger sex change in groupers","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Testicular inducing steroidogenic cells trigger sex change in groupers"}]},"item_type_id":"2","owner":"6","path":["144"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-10-28"},"publish_date":"2021-10-28","publish_status":"0","recid":"26823","relation_version_is_last":true,"title":["Testicular inducing steroidogenic cells trigger sex change in groupers"],"weko_creator_id":"6","weko_shared_id":-1},"updated":"2023-05-15T20:11:08.669025+00:00"}